Efficacy of time restricted eating and economic behavioral intervention in reducing fasting plasma glucose, HbA1c, and cardiometabolic risk factors compared to time restricted eating alone or usual care in patients with prediabetes: A randomized controlled trial
Phase 3
Recruiting
- Conditions
- Impaired fasting glucose Time restricted eatingimpaired glucose tolerence
- Registration Number
- TCTR20210520002
- Lead Sponsor
- ational Research Council of Thailand (NRCT)
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- All
- Target Recruitment
- 114
Inclusion Criteria
impaired fasting glucose (100-125 mg/dL) or abnormal HbA1c (5.7-6.49%)
age 18-65 years
BMI more than 25 kg/m2
Exclusion Criteria
1. Currently on ketogenic diet or vegeterian diet
2. Currently on TRE
3. Shift work
4. Weight change more than 5 kg in 3 months
5. Having medication which has to be taken at early morning or at night
6. Smoking
7. Breast feeding
8. Psychological disorder excluding depression
9. Having medications which affect weight and blood sugar
10. History of bariatric surgery
11. Impaired nutrient absorption
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Fasting blood sugar 4,8,12 weeks hexokinase glucose-6 phosphate dehydrogenase and turbid metric inhibition immunoassay ,HbA1C 4,8,12 weeks hexokinase glucose-6 phosphate dehydrogenase and turbid metric inhibition immunoassay
- Secondary Outcome Measures
Name Time Method Body weight 4,8,12 weeks weight measurement (kg) ,Systolic blood pressure 4,8,12 weeks mmHg,Diastolic blood pressure 4,8,12 weeks mmHg,Fasting insulin 4,8,12 weeks mIU/mL,serum triglyceride 4,8,12 weeks mg/dL ,Total cholesterol 4,8,12 weeks mg/dL,LDL-C 4,8,12 weeks mg/dL,HDL-C 4,8,12 weeks mg/dL ,high sensitivity C-reactive protein 4,8,12 weeks mg/dL