Early Prevention of Childhood Obesity: an Active Pregnancy
试验速览
- 阶段
- 不适用
- 入组人数
- 1,100
- 试验地点
- 2
- 主要终点
- Placenta measurements
研究概览
简要总结
The main aim of this study was to examine the effect of a supervised physical exercise program on the prevention of childhood obesity and its impact on the motor development of the offspring.
详细描述
The environment where the fetus growths up is essential for the risk of developing some diseases in later life, such as obesity. Exercise has showed being useful in the prevention on excessive maternal weight gain which is linked to fetus weight.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Prevention
- 盲法
- Single (Investigator)
入排标准
- 年龄范围
- 18 Years 至 45 Years（Adult）
- 性别
- Female
- 接受健康志愿者
- 是
入选标准
- •Being healthy and able to exercise following American College of Obstetricians and Gynecologists (ACOG) guidelines
- •Being able to communicate in spanish
- •Giving birth at Hospital Universitario de Torrejón, hospital Universitario de Puerta de Hierro and Hospital Universitario Severo Ochoa (Madrid).
排除标准
- •Multiparity
- •Obstetrician complications
- •Being interested in the study after 16 weeks
- •Not being regular in physical exercise program
- •Younger than 18 years old
研究组 & 干预措施
Control
Sedentary pregnant women
Exercise group
Supervised physical conditioning program of three 55-60 minute sessions per week during whole pregnancy (from week 9 to 38). Each session consists of 25-30 minutes of cardiovascular exercise,10 minutes of specific exercises (strength and balance exercises), and 10 minutes of pelvic floor muscles training
Aerobic activity was prescribed at light to moderate intensity, aiming for 55-60% of heart rate reserve. All subjects wore a heart rate (HR) monitor (Polar FT7) during the training sessions to ensure that exercise intensity was light to moderate
干预措施: A supervised physical exercise program (Behavioral)
结局指标
主要结局
Placenta measurements
时间窗: At delivery
Placenta measurements were collected at labor
Body mass index of the offsprings
时间窗: 0-24 postpartum months
Body mass index was measured several times from 0 to 24 months
Fetus body composition
时间窗: 0-24 postpartum months
Fetus body composition (percentage of fat) was measured several times from 0 to 24 months
Glycemia level of the offsprings
时间窗: 0-24 postpartum months
Glycemia level of the offsprings was measured until 24 months
Recovery time to pre-gestational weight
时间窗: 6-12 postpartum months
The time needed to recovery the pre-gestational weight was assessed.
Changes in Baby motor development
时间窗: 0-24 postpartum months
Baby motor development was measured after delivery
Changes from baseline in maternal quality of life
时间窗: up to 36 weeks
Maternal quality of life was measured during and after pregnancy
Change from baseline in Maternal gestational weight gain
时间窗: 40-42 weeks of gestation
Maternal weight gain during pregnancy
Postpartum depression
时间窗: 0-12 postpartum months
The level of maternal depression was measured after delivery
Change from baseline in Body image satisfaction
时间窗: up to 36 weeks
Body image satisfaction was measured during and after pregnancy
次要结局
- Maternal outcomes(At delivery)
- Control of physical activity(up to 10 weeks)
- Changes from delivery in Health of the offspring(0-24 postpartum months)
- Fetus outcomes(At delivery)
研究者
María Perales Santaella
PhD student
Technical University of Madrid