Comparison of pioglitazone with sitagliptin effect in diabetes melitus
Not Applicable
- Conditions
- diabetes.E10-E14
- Registration Number
- IRCT2016112631104N1
- Lead Sponsor
- Vice Chancellor for research of Lorestan University of Medical Sciences
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete
- Sex
- All
- Target Recruitment
- 60
Inclusion Criteria
patients with type 2 diabetes who are older than 18 years treated with 1500 mg metformin and 10-20mg sulfonylureas per day are included in the study. These patients should have HbA1c greater than 7 and fasting glucose greater than 126 mg / dL.
Exclusion criteria:
1) patients who have type 1 diabetes,
2) known case of heart disease and exertional dyspnea, grade 3 and 4
3) kidney disease (GFR <30),
4) ALT / AST more than 3 times normal
Exclusion Criteria
Not provided
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method FPG, HbA1c. Timepoint: Before and three months after intervention. Method of measurement: mg/dl, %.
- Secondary Outcome Measures
Name Time Method Insulin, HOMA index, weight, HDL, TG, LDL, blood pressure. Timepoint: Before and three months after intervention. Method of measurement: Kg, mg/dl, mg/dl, mg/dl, mmHg.