Thai Red Cross AIDS Research Centre (TRC-ARC)
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 6,000
- 试验地点
- 1
- 主要终点
- To determine the uptake of HIV testing among MSM and TG as a result of the community-based Test and Treat approach
研究概览
简要总结
HIV counseling and testing, risk reduction counseling, provision of condoms and lubricants Same-day result HIV testing along with pre-test and post-test counseling, including risk reduction counseling, will be provided according to the standard practice at each study site at enrollment and every 6 months in HIV-negative participants. HIV-negative participants can also access non-occupational post-exposure prophylaxis service and symptomatic STD service if these are available at study sites. HIV-positive participants will also receive risk reduction counseling every 3 months. Condoms and lubricants will be provided free of charge.
详细描述
This study is a prospective observational cohort study that will enroll up to 6,000 Thai MSM and TG from drop-in centers in Bangkok, Chiang Mai, Chonburi and Songkhla. Each participant will have HIV testing at baseline and will be followed up for 18 months.
HIV-negative participants will be asked to have HIV re-testing every 6 months. HIV-positive participants will have POC CD4 testing and ART initiation regardless of CD4 count will be offered. Those who accept ART will be followed up at week 2, week 4, month 2, month 3 and every 3 months thereafter. Those who deny ART will be followed up every 3 months.
Uptake of HIV re-testing will be determined. Access to POC CD4 testing and acceptability of ART initiated at HIV diagnosis regardless of CD4 count along with ART adherence will also be determined.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Years 至 90 Years（Adult, Older Adult）
- 性别
- Male
- 接受健康志愿者
- 是
入选标准
- •Thai national
- •Age >18 years
- •Men or transgender women who report unprotected anal intercourse with a man at least one time in the past 6 months
- •Not known to be HIV-positive, i.e., never tested for HIV or previous HIV test(s) negative
- •Willing to participate in the study
- •Provide written informed consent
排除标准
- •Known HIV-positive serostatus
结局指标
主要结局
To determine the uptake of HIV testing among MSM and TG as a result of the community-based Test and Treat approach
时间窗: 36 months
1. Increase in the number of individuals tested who have not previously had an HIV test 2. Increase in the number of HIV-positive individuals tested who did not previously know their HIV status 3. Increase in the proportion of HIV-negative individuals who are retested at least twice a year, every six months
次要结局
未报告次要终点