NCT00763217已完成不适用
Characterization of Clinical, Biological and Pharmacological Markers of Stroke Outcome
University Hospital, Lille1 个研究点 分布在 1 个国家目标入组 550 人开始时间: 2005年6月1日最近更新:
适应症
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 550
- 试验地点
- 1
- 主要终点
- severity of stroke measured by NIH severity score
研究概览
简要总结
In a previous suty, we have demonstrated that prior transient ischemic attack, treatment lipid-lowering drug or physical activity are associated to a better outcome of stroke. The aim of the study is to understand the mechanisms of this preventive neuroprotection by establishing link between biomarkers and preventive and neuroprotective measures.To answer to the question, we conduct a cohort study of stroke patients.
详细描述
In the cohort, the severity of stroke (NIHSS) will be correlated with :
- clinical factors,
- pharmacological factors,
- biological factors (inflammatory markers, hemostasis...)
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 年龄范围
- 40 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •ischemic or hemorrhage stroke
- •hemispheric stroke
- •stroke dating from less 48h
排除标准
- •non hemispheric stroke
- •malformative intracranial hemorrhage
- •traumatic intracranial hemorrhage
- •subarachnoidal hemorrhage
结局指标
主要结局
severity of stroke measured by NIH severity score
时间窗: inclusion, day7, month3, year3
次要结局
- clinical, pharmacological and biological (metabolic, inflammation, hemostasis...) cognitive status(inclusion and year3)
研究者
研究点 (1)
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