Characterization of Clinical, Biological and Pharmacological Markers of Stroke Outcome
Overview
- Phase
- Not Applicable
- Intervention
- Not specified
- Conditions
- Stroke
- Sponsor
- University Hospital, Lille
- Enrollment
- 550
- Locations
- 1
- Primary Endpoint
- severity of stroke measured by NIH severity score
- Status
- Completed
- Last Updated
- 10 years ago
Overview
Brief Summary
In a previous suty, we have demonstrated that prior transient ischemic attack, treatment lipid-lowering drug or physical activity are associated to a better outcome of stroke. The aim of the study is to understand the mechanisms of this preventive neuroprotection by establishing link between biomarkers and preventive and neuroprotective measures.To answer to the question, we conduct a cohort study of stroke patients.
Detailed Description
In the cohort, the severity of stroke (NIHSS) will be correlated with : * clinical factors, * pharmacological factors, * biological factors (inflammatory markers, hemostasis...)
Investigators
Eligibility Criteria
Inclusion Criteria
- •ischemic or hemorrhage stroke
- •hemispheric stroke
- •stroke dating from less 48h
Exclusion Criteria
- •non hemispheric stroke
- •malformative intracranial hemorrhage
- •traumatic intracranial hemorrhage
- •subarachnoidal hemorrhage
Outcomes
Primary Outcomes
severity of stroke measured by NIH severity score
Time Frame: inclusion, day7, month3, year3
Secondary Outcomes
- clinical, pharmacological and biological (metabolic, inflammation, hemostasis...) cognitive status(inclusion and year3)