Evaluation and Monitoring of the Protocol for the Management of Post Operative Atrial Fibrillation Based on Intravenous Beta-blockers in Cardiac Surgery
Overview
- Phase
- Not Applicable
- Intervention
- Not specified
- Conditions
- Post Operative Atrial Fibrillation
- Sponsor
- University Hospital, Brest
- Enrollment
- 54
- Locations
- 1
- Primary Endpoint
- Heart Rate
- Status
- Completed
- Last Updated
- 4 years ago
Overview
Brief Summary
Objectives The aims of this study is to evaluate the efficacy and tolerance of our post-operative AF management protocol after cardiac surgery, including beta-blockers, digoxin, amiodarone.
Methods This study concerns patients From brest university Hospital who underwent cardiac surgery between November 2019 and November 2021. Patients with a previous history of atrial arrhythmias were excluded. The primary endpoint is assess effectiveness of service protocol to maintain cardiac frequency below. 110 bpm. The secondary endpoints included hemodynamic tolerance and outcomes.
Detailed Description
Background Atrial fibrillation (AF) is the most common complication after open heart surgery. Its reported incidence is about 30%, and it is associated with a significant increase rate of thromboembolic events, respiratory failure, a longer lenght of stay in hospital and mortality. (1 ;2) Gillinov's study has shown equivalent effectiveness of a rhythm control and rate control strategy, in AF patients after cardiac surgery, with increased side effects in patients treated with rhythm control agents. (3) The introduction of beta-blockers can be poorly tolerated hemodynamically in patients hospitalized in intensive care unit, unless untroducing a cardio-selective beta-blocker.. Methods Patients who underwent a cardiac surgery from Novembre 2019 to Novembre 2021 were included. Patients with a previous history of atrial arrhythmias were excluded. The primary endpoint is assess effectiveness of service protocol to maintain cardiac frequency below. 110 bpm. The secondary endpoints included hemodynamic tolerance and outcomes.
Investigators
Eligibility Criteria
Inclusion Criteria
- •POAF after cardiac surgery non-opposition formulated
Exclusion Criteria
- •pregnant woman opposition hemodynamic unstability with inotropic drugs or CI\<2 L/min/m2
Outcomes
Primary Outcomes
Heart Rate
Time Frame: 72 hours (3 days)
HR \< 110 BPM
Secondary Outcomes
- sinusal Rythm(72hours ( 3 days))