Atural history of Peri-pancreatic cOLlEctiONs in acute pancreatitis based on assessment of content with CECT and MRI.
Completed
- Conditions
- pancreatitis10015674
- Registration Number
- NL-OMON33664
- Lead Sponsor
- Sint Antonius Ziekenhuis
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- Not specified
- Target Recruitment
- 25
Inclusion Criteria
• Age 18 years or above
• Acute pancreatitis: upper abdominal pain and serum lipase and/ or amylase levels 3 times the upper level of normal
• Written informed consent
• Patients with peripancreatic fluid collections on CECT > 3 cm in short axis.
Exclusion Criteria
• History or imaging signs of chronic or *acute on chronic* pancreatitis
• AP due to malignancy
• Pregnancy
• Contraindication for MRI imaging (for example pacemaker)
• Incapacitated subjects
Study & Design
- Study Type
- Observational non invasive
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method <p>The primary endpoint is the amount of solid debris as seen on initial MRI in<br /><br>relationship to the absorption rate of these collections.</p><br>
- Secondary Outcome Measures
Name Time Method <p>• Infectious complications (bacteremia, pneumonia, infected necrosis).<br /><br>• Length of hospital stay<br /><br>• Need for ICU admission<br /><br>• New onset organ failure (onset, extent and duration, see definitions section)<br /><br>• Length of ICU stay<br /><br>• Need for percutaneous drainage<br /><br>• Need for surgical or endoscopical necrosectomy<br /><br>• Quality of Life.</p><br>