Estimating Usual Iodine Intake From Spot Urinary Iodine Concentrations
- Conditions
- Iodine Deficiency
- Registration Number
- NCT03602404
- Lead Sponsor
- Swiss Federal Institute of Technology
- Brief Summary
The overall objective of this study is to develop a reliable method to obtain habitual iodine intakes from spot urinary iodine concentration (UIC) and to assess the prevalence of inadequate iodine intake in school-age children and women of reproductive age. We will evaluate different methods to estimate iodine intake from UIC and estimate the prevalence of inadequate and excess iodine intake in UIC studies conducted in populations with low, adequate and high iodine intakes using the the established estimated average requirement (EAR)/Tolerable Upper Intake Level (UL) cut-point method.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- All
- Target Recruitment
- 1592
- lived in study area >= 12 months
- no reported intake of Amiodarone
- no history of thyroid dysfunction / goiter (past & present)
- no exposure to iodine containing contrast agents within the last 12 months
Second arm: Women aged 18 - 49, exclusion / inclusion criteria apply, plus non-pregnant, non-lactating.
Not provided
Study & Design
- Study Type
- OBSERVATIONAL
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Estimated iodine intake 17 months Estimated daily iodine intake of the study population derived from urinary iodine and creatinine concentrations measured in spot urine samples
- Secondary Outcome Measures
Name Time Method Urinary iodine concentration 17 months Measured in spot urine samples and 24 h urine collections
Urinary creatinine concentration 17 months Measured in spot urine samples and 24 h urine collections
Trial Locations
- Locations (2)
University of Papua New Guinea
🇵🇬Sia, Morobe, Papua New Guinea
Almazov Medical Research Center
🇷🇺Saint Petersburg, Russian Federation