Effect of a Plant Based Nootropic on Perceptual Decision Making.

Not Applicable

Completed

• Conditions: Cognitive Enhancement

• Registration Number: NCT06689644
• Lead Sponsor: University of Leeds

Brief Summary

Nootropics are a group of medicinal substances purported to improve important cognitive functions such as learning, focus and memory. Many of these substances have demonstrated beneficial effects on cognitive performance and overall health. However, a thorough understanding of how these substances and their synergistic effects in the form of a supplement may benefit fundamental brain processes is currently lacking. In the current study, we will investigate the effects of a plant-based, nootropic supplement (https://uk.mindlabpro.com/) on perceptual decision-making (i.e. the ability to make rapid decisions based on sensory stimuli) in healthy adult participants.

Detailed Description

Participants will perform a computerised cognitive task assessing their perceptual decision-making pre- and post- 60 days of continuous supplementation with either a plant-based nootropic supplement (Mind Lab pro) or placebo. During testing, electroencephalography (EEG) signals will be captured simultaneously.

Study Timeline

• Study Start: 2023-10-23
• Primary Completion: 2024-03-06
• Study Completion: 2024-06-01
• Status Verified: 2024-11
• Study First Submitted: 2024-11-13
• Study First Submitted QC: 2024-11-13
• Last Update Submitted: 2024-11-13
• Study First Posted: 2024-11-14
• Last Update Posted: 2024-11-14

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 37

Inclusion Criteria

• Eligibility screening of participants was guided by the following inclusion criteria: (i) be between 20-59 years old, (ii) be right-handed and (iii) be able to cease taking other dietary supplements for two months.

Exclusion Criteria

• Exclusion criteria included: (i) currently consuming a nootropic supplement, (ii) any known musculoskeletal, or neurological medical conditions or cognitive impairments (iii) have a known diagnosis of epilepsy/history of seizures and (iv) have a known hearing or visual condition that affects daily life function.

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Primary Outcome Measures

Name	Time	Method
Perceptual decision-making performance	Pre- and post- 60 days of supplementation	Choice accuracy and reaction times

Secondary Outcome Measures

Name	Time	Method
Brain network interdependencies	Pre- and post- 60 days of supplementation	Patterns extracted from brain signals using electroencephalography

Trial Locations

Locations (1)

Faculty of Biological sciences; 🇬🇧 Leeds, United Kingdom