Rehabilitation of attention following traumatic brain injury: A model for methylphenidate

Not Applicable

Completed

• Conditions: Traumatic brain injury; Physical Medicine / Rehabilitation - Other physical medicine / rehabilitation

• Registration Number: ACTRN12607000503426
• Lead Sponsor: Ms. Catherine Willmott

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2007-10-04
• Last Update Posted: 13 January 2020

Recruitment & Eligibility

• Status: Completed
• Sex: All
• Target Recruitment: 40

Inclusion Criteria

History of moderate-severe traumatic brain injury sustained within the previous 12 months
-Current inpatient on Acquired Brain Injury (ABI) ward of Epworth Rehabilitation
-Demonstrated attentional impairment as indicated on the Symbol Digit Modalities Test
-Adequate physical and cognitive abilities and understanding of English to complete neuropsychological tasks

Exclusion Criteria

-Past neurological history
-Past treatment for drug/alcohol dependence
-Current treatment with psychoactive medications likely to interact with methylphenidate

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Reaction time on computerised visuo-spatial choice RT tasks[On the 6 trial days over the 2 week period];Performance on standardised neuropsychological measures:<br>Symbol Digit Modalities Test,<br>Ruff 2 & 7 Selective Attention Test,<br>Letter Number Sequencing (from WAIS-III)[On the 6 trial days over the 2 week period];Score on the Rating Scale of Attentional Behaviour as rated by Allied Health Therapists[On the 6 trial days over the 2 week period]

Secondary Outcome Measures

Name	Time	Method
Measurement of drug effects on vital signs:<br>pulse, blood pressure, mean arterial pressure[On the 6 trial days over the 2 week period];Measurement of drug effects on Side Effects Monitoring Form[On the 6 trial days over the 2 week period]