PSO17CSF Study in Motor Neuron Disease

Phase 1

Recruiting

• Conditions: D016472; motor neuron disease

• Registration Number: JPRN-jRCT2011220046
• Lead Sponsor: Kudo Kohsuke

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2023-03-25
• Last Update Posted: 1 April 2024

Recruitment & Eligibility

• Status: Recruiting
• Sex: All
• Target Recruitment: 30

Inclusion Criteria

(1) Over 18 years old when informed consent is obtained.
(2) Patients with motor neuron disease.
(3) The patients scheduled for lumbar puncture.
(4) Written informed consent is obtained after sufficient explanation and full understanding.

Exclusion Criteria

(1) Contraindication for MRI such as metallic implant, tattoo in the body.
(2) Severe lumbar canal stenosis.
(3) Currently enrolled in another research.
(4) Previous history of drug allergy
(5) Serious disease of liver, kidney, heart, etc.
(6) Current or planned pregnancy.
(7) The patients with lesions on MRI scan in the previous observation period (except when the investigator determines that there is no problem with participation in the clinical trial).
(8) Any other reason judged by a clinical trial doctor that renders the candidate unsuitable for this clinical trial.

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
safety

Secondary Outcome Measures

Name	Time	Method
change in MRI signal intensity.<br>safety