Differential Metabolic Effects of Fenofibrate and Fatty Acid

Phase 4

Completed

• Conditions: Hypertriglyceridemia
• Interventions: Drug: fenofibrate, fatty acid, placebo

• Registration Number: NCT01003847
• Lead Sponsor: Gachon University Gil Medical Center

Brief Summary

The investigators hypothesize that fenofibrate and fatty acid may have different metabolic effects in hypertriglyceridemic patients

Detailed Description

Not available

Study Timeline

• Study First Submitted: 2009-10-28
• Study First Submitted QC: 2009-10-28
• Study First Posted: 2009-10-29
• Study Start: 2009-11
• Primary Completion: 2010-09
• Study Completion: 2010-09
• Status Verified: 2010-10
• Last Update Submitted: 2011-05-09
• Last Update Posted: 2011-05-10

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 150

Inclusion Criteria

• hypertriglyceridemia

Exclusion Criteria

• Overt liver disease Chronic renal failure Hypothyroidism Myopathy Uncontrolled diabetes Severe hypertension

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
fatty acid	fenofibrate, fatty acid, placebo	drug
fenofibrate	fenofibrate, fatty acid, placebo	-
Placebo	fenofibrate, fatty acid, placebo	-

Primary Outcome Measures

Name	Time	Method
flow-mediated dilation	8 weeks of treatment

Secondary Outcome Measures

Name	Time	Method
insulin resistance	8 weeks of treatment

Trial Locations

Locations (1)

Gil Medical Center; 🇰🇷 Incheon, Korea, Republic of