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Balance Training for Fall Reduction in COPD

Not Applicable
Terminated
Conditions
Copd
Fall Patients
Interventions
Other: Balance training
Other: Pulmonary rehab
Registration Number
NCT02995681
Lead Sponsor
West Park Healthcare Centre
Brief Summary

People living with Chronic Obstructive Pulmonary Disease (COPD) have problems with their balance and a high incidence of falls compared to those of a similar age. Pulmonary rehabilitation is recommended for people with COPD, however, these training programs do not typically include balance training or fall prevention strategies. In this study, patients with COPD who report problems with their balance or have had a fall in the last two years will be assigned to a treatment group (balance training plus pulmonary rehabilitation) or control group (standard pulmonary rehabilitation). We will record the number of falls using monthly diaries and evaluate patient's balance, strength, confidence and quality of life.

Detailed Description

Chronic obstructive pulmonary disease (COPD) is a leading cause of morbidity and mortality in Canada. In addition to lung impairment, secondary effects of the disease are well established including impairments in muscle function and exercise capacity. However, individuals with COPD also have marked deficits in balance and an increased risk of falls with a 3-5 times higher annual fall rate than those of similar age. The underlying mechanisms remain unclear, but several factors have been implicated including decreased physical activity, muscle weakness, altered trunk mechanics, comorbidities, hypoxemia and proprioceptive deficits. Given this unique impairment profile, tailored approaches to balance training and fall prevention are needed in COPD.

Pulmonary rehabilitation (PR) is an integral therapeutic intervention for individuals with COPD. The program typically consists of supervised exercise, disease-specific education, and psychological and social support. Balance training and fall prevention strategies are not currently included in international guidelines for PR and few programs include any balance assessment. We have previously shown that the exercise component of traditional PR has minimal effect on measures of balance and fall risk. We then conducted an RCT to examine the effects of balance training alongside PR, which specifically addressed the profile of balance deficits we had identified in COPD. Tailored balance training alongside PR results in clinically important improvements in balance performance compared to PR alone. Given these results, we now have the opportunity to build on our existing experience to test the effect of the intervention on falls.

The purpose of this study is to establish the efficacy of a tailored balance exercise program for reducing falls in individuals with COPD enrolled in PR. If participation in tailored balance training decreases falls compared to usual PR, this approach will represent an innovative and potential cost-saving strategy to prevent falls and reduce associated healthcare utilization in COPD. Our results will be relevant for guiding clinical and policy-based decision making, given the large population of individuals with COPD and the potential for severe consequences of falls in this population.

The primary objective of this study is to evaluate the long-term effects of tailored balance exercise on the rate of falls in individuals with COPD enrolled in PR. Secondary objectives are to determine 1) the long-term effects of the program on measures of balance, balance confidence and muscle strength; and 2) the cost-utility of the program.

Recruitment & Eligibility

Status
TERMINATED
Sex
All
Target Recruitment
258
Inclusion Criteria
  • a physician diagnosis of COPD based on GOLD criteria; a self-reported decline in balance, a fall within the last two years or a recent near fall; and an ability to provide written informed consent
Exclusion Criteria
  • severe cognitive impairment (dementia, neurological condition) an inability to communicate because of language skills (aphasia, non-English speaking), or evidence of a neurological or musculoskeletal condition that severely limits mobility and postural control (e.g. cerebrovascular accident, Parkinson's Disease, amputation) and may jeopardize their safety or influence their balance.

Study & Design

Study Type
INTERVENTIONAL
Study Design
PARALLEL
Arm && Interventions
GroupInterventionDescription
Pulmonary rehab and balance trainingPulmonary rehabThe intervention group will receive standard pulmonary rehab plus additional balance training.
Pulmonary rehab and balance trainingBalance trainingThe intervention group will receive standard pulmonary rehab plus additional balance training.
Pulmonary rehabPulmonary rehabThe control group will receive pulmonary rehab only and a pulmonary rehab home program (walking and lower extremity resistance exercises) upon discharge from pulmonary. They will also receive the same monthly phone calls and three home visits at three, six and nine months to ensure proper technique and progression.
Primary Outcome Measures
NameTimeMethod
Number of falls12 months

Number of falls will be measured using monthly falls diaries

Secondary Outcome Measures
NameTimeMethod
Balance Evaluation Systems Test (BESTest)Baseline (pre pulmonary rehab), 8 weeks (post pulmonary rehab), 12 months

Clinical measure of balance

Activities Specific Balance Confidence ScaleBaseline (pre pulmonary rehab), 8 weeks (post pulmonary rehab), 12 months

Balance confidence questionnaire

30 Second Repeated Chair Stand TestBaseline (pre pulmonary rehab), 8 weeks (post pulmonary rehab), 12 months

Functional lower body strength test

European Quality of Life 5-Dimension Questionnaire (EQ-5D-5L)Baseline (pre pulmonary rehab), 8 weeks (post pulmonary rehab), 6 months, 12 months

Health status questionnaire

Berg Balance ScaleBaseline (pre pulmonary rehab), 8 weeks (post pulmonary rehab), 12 months

Clinical measure of balance

Trial Locations

Locations (10)

James Cook University Hospital

🇬🇧

Middlesbrough, North Yorkshire, United Kingdom

School of Health Sciences, University of Aveiro

🇵🇹

Aveiro, Portugal

Western Health

🇦🇺

Saint Albans, Victoria, Australia

Royal Prince Alfred Hospital

🇦🇺

Camperdown, New South Wales, Australia

Alfred Health

🇦🇺

Melbourne, Victoria, Australia

G.F. Macdonald Centre for Lung Health

🇨🇦

Edmonton, Alberta, Canada

St. Paul's Pulmonary Rehab Program

🇨🇦

Vancouver, British Columbia, Canada

Colchester East Hants Health Authority

🇨🇦

Truro, Nova Scotia, Canada

Ottawa Hospital Rehabilitation Centre

🇨🇦

Ottawa, Ontario, Canada

West Park Healthcare Centre

🇨🇦

Toronto, Ontario, Canada

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