Comparison of three drugs for reducing Postoperative pain in Lower Abdominal Surgeries under Spinal Anesthesia
Phase 2
- Conditions
- Health Condition 1: O- Medical and Surgical
- Registration Number
- CTRI/2024/04/065076
- Lead Sponsor
- Sri Guru Ram Das Institute of Medical Sciences and research
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- ot Yet Recruiting
- Sex
- Not specified
- Target Recruitment
- 0
Inclusion Criteria
1 Physical status based on ASA Grade 1 and Grade 2.
2 Patients posted for lower abdominal surgeries under spinal anaesthesia. appendicectomy, herniorrhaphy, hernioplasty,, excision of lipoma, fistulectomy, haemorrhoidectomy, hydrocoele, varicocoele, Perianal abscess drainage,fissurectomy etc
Exclusion Criteria
1.Patients with uncontrolled co-existing systemic or metabolic diseases.
2. Patients with any liver disease
3. Pregnant and lactating women.
4. Patients with narcotic addiction.
5. Patients with known hypersensitivity to the study drugs
6. Patient’s refusal
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method To compare efficacy of Flupirtine maleate, Tapentadol <br/ ><br>hydrochloride and Tramadol hydrochloride for post operative analgesia in lower <br/ ><br>abdominal surgeries performed under spinal anaesthesia in terms of <br/ ><br>1. Duration of analgesia after the study drug is given <br/ ><br>2. Frequency of doses required of the study drug <br/ ><br>3. VAS assessment <br/ ><br>4. Frequency of rescue analgesiaTimepoint: after 3 hours of start of surgery, after that 3 hourly for first 12 hours and 6 hourly thereafter till 48 hours.
- Secondary Outcome Measures
Name Time Method Incidence of adverse effects during the study periodTimepoint: after 3 hours of start of surgery, till 48 hours.