Biobank Based on the i-Share Student Cohort
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 1,997
- 试验地点
- 1
- 主要终点
- The acquisition date of blood samples
研究概览
简要总结
The bio-Share project aims at collecting blood samples in students participating in the i-Share cohort (www.i-share.fr). Investigators aim at setting up a platform that will enable investigators in the future to study biological determinants of conditions that affect young adults and to test certain hypotheses on the pathophysiology and mechanisms underlying diseases occurring both at a young age and later in life (as early exposures may also impact late onset diseases)
详细描述
The i-Share cohort was set up to study various important aspects of students' health and to better understand early mechanisms contributing to the occurrence of common diseases representing an important public health burden. The i-Share cohort is funded by an "investment for the future grant" from the French National Research Agency (ANR-10-COHO-05-01) with the aim to recruit 30000 students at the University of Bordeaux, and a few additional partner universities in France and abroad (www.i-share.fr).
The bio-Share study is a biological repository embedded within the i-Share study, aiming at collecting blood samples (for genetic analyses as well as measurement of other biomarkers) from a subset of 2000 i-Share participants volunteering for this ancillary project.
The goal is to set up a platform that will enable investigators in the future to study biological determinants of conditions that affect young adults and to test certain hypotheses on the pathophysiology and mechanisms underlying diseases occurring both at a young age and later in life (as early exposures may also impact late onset diseases).
The biobank will comprise the following biological materials: plasma, serum, whole blood, red blood cells, DNA, RNA. Levels of fasting glucose and lipid levels (total cholesterol, HDL-cholesterol, LDL-cholesterol, triglycerides) will be returned to participants.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •Be an i-Share participant in Bordeaux
- •Being aged 18 years or more
- •Being affiliated or beneficiary of a social security
- •Having filled out the first online i-Share questionnaire
- •Having signed a written informed consent
排除标准
- •Pregnant or breastfeeding women,
- •Persons who cannot personally give their consent and adults under guardianship.
结局指标
主要结局
The acquisition date of blood samples
时间窗: Day 1
The number of the aliquots for each of the stored biological samples
时间窗: Day 1
The total volume of the aliquots for each of the stored biological samples
时间窗: Day 1
次要结局
- Total cholesterol (fasting)(Day 1)
- Low-density lipoprotein-cholesterol (fasting)(Day 1)
- Glucose (fasting)(Day 1)
- High-density lipoprotein cholesterol (fasting)(Day 1)
- Triglycerides (fasting)(Day 1)