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Clinical Trials/NCT05061186
NCT05061186
Completed
Not Applicable

Effects of Resistive Expiratory Muscle Training on Pulmonary Functions in Patients With COPD Patients

Riphah International University1 site in 1 country74 target enrollmentOctober 10, 2021
ConditionsCOPD

Overview

Phase
Not Applicable
Intervention
Not specified
Conditions
COPD
Sponsor
Riphah International University
Enrollment
74
Locations
1
Primary Endpoint
Maximum expiratory pressure
Status
Completed
Last Updated
4 years ago

Overview

Brief Summary

  • To determine effects of resistive expiratory muscle training on pulmonary functions in Chronic obstructive pulmonary disease (COPD) patients
  • To determine effects of resistive expiratory muscle training on maximum expiratory pressure in COPD patients
  • To determine effects of resistive expiratory muscle training on quality of life in COPD patients
Registry
clinicaltrials.gov
Start Date
October 10, 2021
End Date
January 15, 2022
Last Updated
4 years ago
Study Type
Interventional
Study Design
Parallel
Sex
All

Investigators

Responsible Party
Sponsor

Eligibility Criteria

Inclusion Criteria

  • COPD patients (GOLD criteria - moderate, moderately severe)
  • Borg scale \< 4

Exclusion Criteria

  • Patients with Orthopedic disease
  • Neurological disease,
  • Cognitive impairment (Mini-Mental State Examination \< 22) ,
  • Heart diseases,
  • Pulmonary fibrosis
  • Obstructive sleep apnea syndrome.
  • Acute and chronic infections

Outcomes

Primary Outcomes

Maximum expiratory pressure

Time Frame: 6 weeks

Maximum expiratory pressure (MEP) measures the maximum positive pressure that can be generated from one expiratory effort starting from total lung capacity (TLC) . Changes will be assessed from the baseline and at the end of the intervention after 6 weeks

St George's Respiratory Questionnaire

Time Frame: 6 Week

This is a specific respiratory instrument developed for patients with COPD. Its validity, reproducibility and response to change over time have been demonstrated. It has three components: symptoms, activity and impact. The responses to the items can be aggregated into an overall score and three sub-scores for symptoms, activity and impact in the range 0-100%. Higher scores indicate a poorer quality of life).Changes will be assessed from the baseline and at the end of the intervention after 6 weeks

Forced Expiratory Volume in 1 second (FEV1)

Time Frame: 6 Week

Changes from the Baseline, the digital spirometer is used in clinical setting to analyze Forced Expiratory Volume in 1 second FEV1 in Liters

Forced vital Capacity (FVC)

Time Frame: 6 week

Changes From the Baseline, the digital spirometer is used in clinical setting to analyze Forced vital Capacity in Liters.

Peak Expiratory Flow (PEF)

Time Frame: 6 Week

Changes from the Baseline, the digital spirometer is used in clinical setting to analyze peak expiratory flow PEF in Liter/second.

Volume of Lungs inflation

Time Frame: 6 week

The incentive spirometer is a device that encourages patients with visual and other positive feedback, to maximally inflate their lungs and sustain that inflation. It is a common mode of postoperative respiratory therapy and involves deep breathing facilitated by a simple mechanical device. Maximal volume of lung inflation is thought to open collapsed alveoli and thereby prevent and resolve atelectasis. When all three balls reached their column tops, it indicated that the subject was able to generate inspiratory airflow of 1200 ml/ml. When only two balls reached their column tops, it indicated that the subject generated 900 ml/min. When only one ball reached their column tops, it indicated that the subject could only generate 600 ml/min. Changes will be assessed from the baseline and at the end of the intervention after 6 weeks

Study Sites (1)

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