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Study of efficacy and safety of Vildagliptin as add-on insulin therapy in T2DM patients

Phase 4
Conditions
Type 2 Diabetes Mellitus
Registration Number
JPRN-jRCT1080222358
Lead Sponsor
ovartis Pharma K.K.
Brief Summary

Not available

Detailed Description

Not available

Recruitment & Eligibility

Sex
All
Target Recruitment
152
Inclusion Criteria

*Confirmed diagnosis of T2DM by standard criteria.
*HbA1c >= 7.0 to <= 10% at Visit 1.
*Age: >= 20 to < 75 years old at Visit 1.
*BMI >= 20 to <= 35 kg/m2 at Visit 1.

Exclusion Criteria

*FPG >= 270 mg/dL (>= 15 mmol/L) at Visit 1.
*Type 1 diabetes, monogenic diabetes, diabetes resulting from pancreatic injury, or secondary forms of diabetes.
*Significant heart diseases
*Hepatic disorder
Other protocol-defined inclusion/exclusion criteria may apply.

Study & Design

Study Type
Interventional
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
Change from baseline in glycosylated hemoglobin (HbA1c) at 12 weeks between treatment groups [Time Frame: Baseline to 12 weeks]<br><br>HbA1c will be performed on a blood sample obtained and measured by HPLC performed at a central laboratory.
Secondary Outcome Measures
NameTimeMethod
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