Investigating the association between clinical and ocular characteristics with the outcomes of corneal collagen cross-linking (CXL)

Phase 2

• Conditions: Keratoconus.; Keratoconus; H18.6

• Registration Number: IRCT20131229015975N4
• Lead Sponsor: Esfahan University of Medical Sciences

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Last Update Posted: 21 May 2019

Recruitment & Eligibility

• Status: Complete
• Sex: All
• Target Recruitment: 85

Inclusion Criteria

Patient satisfaction
keratoconus patients who are newly candidates for corneal collagen cross-linking

Exclusion Criteria

Patients who have any of the following concomitant ocular diseases: diabetic macular edema, age-related macular degeneration.
other corneal diseases
pregnancy, and breastfeeding period

Study & Design

• Study Type: interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Visual acuity. Timepoint: Before surgery and six months after surgery. Method of measurement: Snellen chart.;Corneal power. Timepoint: Before surgery and six months after surgery. Method of measurement: Pentacam imaging.

Secondary Outcome Measures

Name	Time	Method
evels of tear biomarkers. Timepoint: Before surgery and six months after surgery. Method of measurement: The lab using ELISA TEAR IL6 and Tear TNF-a tests.