NL-OMON28825已完成不适用
owering Branched-Chain Amino Acids as aNew Strategy to Improve Insulin Sensitivity
Maastricht UniversityNUTRIMUniversiteitssingel 406229 ER Maastricht+31 43 3881476secretariaat-nutrim@maastrichtuniversity.nl0 个研究点目标入组 16 人开始时间: 待定最近更新:
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 16
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Interventional
入排标准
入选标准
- •1.Patients are able to provide signed and dated written informed consent prior to any study specific procedures
- •2.Women are post-menopausal (defined as at least 1 year post cessation of menses) and aged =45 and =75 years. Males are aged =40 years and =75 years
- •3.Patients should have suitable veins for cannulation or repeated venipuncture
- •4.Caucasians
- •5.BMI: 25-38 kg/m2
- •6.Diagnosed with T2D at least 1.5 years before the start of the study
排除标准
- •1.Previous enrolment in a clinical study with an investigational product during the last 3 months or as judged by the Investigator
- •2.Participate in physical activity more than 3 times a week
- •3.Unstable body weight (weight gain or loss > 5 kg in the last three months)
- •4.Insulin dependent T2D
- •5.Patients with congestive heart failure and and/or severe renal and or liver insufficiency or known sodium retention with oedema
- •6.Patients using Probalan (probenecid), Haldol (haloperidol), Depakene (valproate) or medical products containing corticosteroids
- •7.Men: Hb <8.4 mmol/L, Women: Hb <7.8 mmol/l
- •8. Any contra-indication MRI scanning. These contra-indications include patients with e.g. the following:
- •Central nervous system aneurysm clip
- •Implanted neural stimulator
- •Implanted cardiac pacemaker of defibrillator
- •Cochlear implant
- •Metal containing corpora aliena in the eye or brains
研究者
相似试验
进行中（未招募）
1 期
To boost aminoacid oxidation in diabetestype 2 diabetesEUCTR2018-003176-13-NLMaastricht University16
已完成
2 期
Effects and feasibility of branched chain amino acid combined with exercise in convalescent patients: A crossover trialConvalescent patients after orthopadic surgery, stroke and lower limb amputeeJPRN-UMIN000037903Showa University Fujigaoka Hospital56
Enrolling By Invitation
3 期
The efficacy of adding branched-chain amino acid supplement with home-based exercise for treatment of sarcopenia in cirrhotic patientssarcopenia in cirrhotic patientssarcopenia, cirrhosis, exercise, branched-chain amino acide, BCAA, CPET, skeletal muscle index, SMITCTR20230713008/A10
尚未招募
2 期
The effect of branched-chain amino acid granules to innate immunity in decompensated cirrhosis, A randomized controlled trialLiver CirrhosisDecompensated cirrhosis,Child-Pugh B,C with documented ascitesand MELD score < 20Amino Acids,Branched-ChainImmunity,InnateTCTR20190830005Faculty of Medicine, Prince of Songkla University72
尚未招募
1 期
Effect of Branched-Chain Amino Acids Supplementation on Physical and Cognitive Performance and Biological ResponsesNutritional, Metabolic, EndocrinePACTR202208691866055aboratory of Biochemistry CHU Habib Bourguiba10