A Prospective observational study designed to study the association between preoperative frailty and postoperative delirium in cardiac surgery patients.
试验速览
- 阶段
- 不适用
- 状态
- 招募中
- 发起方
- 入组人数
- 150
- 试验地点
- 1
- 主要终点
- association between preoperative frailty and postoperative delirium in cardiac surgery patients.
研究概览
简要总结
Delirium is frequently seen postoperatively in cardiacsurgery patients, adding up to postoperative mortality and morbidity.
“Delirium is defined as an acute and overt change incognition and attention which may include alteration in consciousness anddisorganized thinking.â€
The unfavorable outcomes that follows post-operativedelirium includes prolonged hospitalization, increased rates of delayedinstitutional discharge, persistent functional and cognitive deficits,increased 30-day and 5-year mortality.This results in a substantial increase incost to the system.
According to current estimates, the incidence ofpostoperative delirium is 1 in 5 cardiac surgery patients .This necessitatespredicting patients susceptible to delirium preoperatively, so as to diagnoseand treat delirium early hence reducing post-operative morbidity.
There are different methods to predict patients susceptibleto delirium; one of such method is assessing frailty.
Frailty is defined as a state of decreased physiologicalreserves due to multisystem decline, which leaves patients in a state ofincreased vulnerability
Frailty consorts with multiple undesirable outcomes likecognitive decline, falls, fractures, and progressive disability in activitiesof daily living.
Presence of frailty increases the risk for post-operativecomplications of cardiac surgery such as inhospital mortality, institutional discharge,and reduced mid-term survival.
In this study, we would be doing a prospective observationalstudy to determine the effect of frailty on postoperative delirium in cardiacsurgery patients.
Frailty would be assessed by using following criteria:
-
The Fried criteria
-
Edmonton Frail Scale
-
Short physical performance battery
-
35-item frailty index
And delirium would be assessed by usingConfusion assessment method (CAM)
研究设计
- 研究类型
- Observational
入排标准
- 年龄范围
- 30.00 Year(s) 至 50.00 Year(s)(—)
- 性别
- All
入选标准
- •Patients undergoing elective cardiac surgery which includes cardiac bypass surgery and valvular heart disease repair surgery.
排除标准
- •Emergency Cardiac surgery.
- •K/C/O psychiatric illness.
- •Patients in whom delirium cannot be assessed reliably like patients with previous stroke, cerebral palsy, severe dementia, severe hearing disabilities, 4) Patients refusal to give consent.
结局指标
主要结局
association between preoperative frailty and postoperative delirium in cardiac surgery patients.
时间窗: 2 weeks
次要结局
未报告次要终点
