Study of the Inflammatory Reaction in Standard vs Single Port Cholecystectomy for Uncomplicated Cholelithiasis
Not Applicable
Completed
- Conditions
- CholelithiasisInflammatory Response
- Interventions
- Other: Single incision laparoscopic cholecystectomyOther: Laparoscopic cholecystectomy
- Registration Number
- NCT01116492
- Lead Sponsor
- G. Hatzikosta General Hospital
- Brief Summary
This is a study of the inflammatory reaction in standard 4 port laparoscopic cholecystectomy vs Single Port Laparoscopic (SIL) cholecystectomy. It is assumed that the reduced trauma in SIL Cholecystectomy causes reduced inflammatory reaction compared to the 4 port laparoscopic cholecystectomy.
- Detailed Description
Two groups of 20 patients each are included in this study. Pre operatively, 6 and 24 hours postoperatively, blood is taken from these patients, it is centrifuged and the plasma is taken. IL-6, a-defensins and CRP are measured for each sample.
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- All
- Target Recruitment
- 40
Inclusion Criteria
- Uncomplicated cholelithiasis
- American Society of Anesthesiologists (ASA) I or II
- No previous operations in upper abdomen
- Body mass index (BMI) <30
Exclusion Criteria
- Cholecystitis
- ASA > II
- BMI>30
- Previous operations in upper abdomen
- Previous operations in intestine
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- PARALLEL
- Arm && Interventions
Group Intervention Description SILS group Single incision laparoscopic cholecystectomy Patients in this group are operated for uncomplicated cholelithiasis with Single Incision Laparoscopic Cholecystectomy Lap Group Laparoscopic cholecystectomy Patients in this group are operated for uncomplicated cholelithiasis with standard 4 port laparoscopic cholecystectomy
- Primary Outcome Measures
Name Time Method
- Secondary Outcome Measures
Name Time Method
Trial Locations
- Locations (1)
"G. Hatzikosta" General Hospital of Ioannina
🇬🇷Ioannina, Greece