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Clinical Trials/NCT03025165
NCT03025165
Completed
Not Applicable

A Comparison of Different Community Models of ART Delivery Amongst Stable HIV+ Patients in Two Urban Settings in Zambia

HIV Prevention Trials Network1 site in 1 country2,526 target enrollmentMay 1, 2017
ConditionsHIV Infections

Overview

Phase
Not Applicable
Intervention
Not specified
Conditions
HIV Infections
Sponsor
HIV Prevention Trials Network
Enrollment
2526
Locations
1
Primary Endpoint
Viral Suppression
Status
Completed
Last Updated
last year

Overview

Brief Summary

The purpose of this study is to compare the virological and clinical outcomes of patients participating in community models of ART delivery to the standard of care in an urban setting in Zambia.

Detailed Description

The outcomes of this study will be measured in a prospective cohort of adult patients enrolled into ART care in two urban communities participating in the HPTN 071 (PopART) trial. The two community models are: 1) adherence clubs, groups of 20-25 stable patients who receive ART care in the community every 3 months, and 2) home-based ART delivery in which a community health worker delivers ART care to an individual at home every 3 months. The standard of care is delivery of ART care at the local clinic.

Registry
clinicaltrials.gov
Start Date
May 1, 2017
End Date
July 22, 2019
Last Updated
last year
Study Type
Interventional
Study Design
Parallel
Sex
All

Investigators

Sponsor
HIV Prevention Trials Network
Responsible Party
Sponsor

Eligibility Criteria

Inclusion Criteria

  • 18 years or older On first-line ART and retained in care for more than 6 months Virologically suppressed World Health Organization (WHO) stage I and II at time of screening Reside within the clinic catchment area Willing to provide written informed consent and accept Community HIV-care Provider (CHiPs) intervention

Exclusion Criteria

  • Not provided

Outcomes

Primary Outcomes

Viral Suppression

Time Frame: One year after beginning participation in the program

Viral suppression at 12 months measured using the standard of care viral load testing equipment currently in place. Viral suppression will be defined according to National guidelines.

Secondary Outcomes

  • Viral suppression at 24 months(Two years after beginning participation in the program)

Study Sites (1)

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