Evaluation of Two Enteral Nutrition Strategies in Mechanically Ventilated Patients

University Hospital, Limoges2 sites in 1 country100 target enrollmentJuly 2002

Conditions-Mechanically Ventilated Patients

Overview

Phase: Not Applicable
Intervention: Not specified
Conditions: -Mechanically Ventilated Patients
Sponsor: University Hospital, Limoges
Enrollment: 100
Locations: 2
Primary Endpoint: Incidence of nutrition failure (diarrhea, ileus, vomiting, aspiration pneumonia, elevated residual gastric volume)
Status: Completed
Last Updated: 17 years ago

Overview Investigators Eligibility Criteria Outcomes Sites Similar Trials

Overview

Brief Summary

The aim of this study is to compare two strategies of early enteral nutrition in terms of efficacy and complications in mechanically ventilated patients.

Registry

clinicaltrials.gov

Start Date

July 2002

End Date

TBD

Last Updated

17 years ago

Study Type

Interventional

Study Design

Parallel

Sex

All

Investigators

Sponsor

University Hospital, Limoges

Eligibility Criteria

Inclusion Criteria

•Adult (\> 18 ans)
•Mechanical ventilation for \> 72 hours
•Planned enteral nutrition
•Informed consent

Exclusion Criteria

•Body Mass Index \< 20 kg/m2
•Enteral nutrition non indicated (ileus, splanchnic ischemia..)
•Shock (use of catecholamines, arterial blood pressure \< 90 mmHg, peripheral hypoperfusion, elevation of lactates \> x 1,5 normal value)
•Contraindications for gastric tube
•Pregnancy
•Previous enrollment in the present study

Outcomes

Primary Outcomes

Incidence of nutrition failure (diarrhea, ileus, vomiting, aspiration pneumonia, elevated residual gastric volume)

Secondary Outcomes

-Measured nutrition amount when compared to theorical nutrition during ICU stay
-Measured nutrition amount when compared to theorical nutrition during the first three days
-Influence of prokinetic drugs on nutrition quality