Feasibility of Virtual Reality Games Using Head-mounted Display on Patients With Brain Disorders

Not Applicable

Completed

• Conditions: Brain Diseases; Upper Extremity Dysfunction
• Interventions: Device: Virtual rehabilitation

• Registration Number: NCT03196739
• Lead Sponsor: Seoul National University Hospital

Brief Summary

Because virtual reality can provide more enriched environment, repetitive goal-oriented tasks, and increased patients' interest and motivation, it is expected to stimulate neuroplasticity of injured brain and promote recovery in patients with brain disorders. On the other hand, immersive virtual reality using a head-mounted display has not yet been attempted in the rehabilitation of patients with brain disorders. In addition to the benefits of existing virtual reality or game rehabilitation, immersive virtual reality can further enhance brain plasticity, such as the effect of mirror therapy or action observation, through self-awareness of the body in the virtual space. The purpose of this study is to investigate the feasibility of applying the immersive virtual reality using a head-mounted display in patients with upper extremity dysfunction due to brain disorders.

Detailed Description

Not available

Study Timeline

• Study Start: 2017-06-20
• Study First Submitted: 2017-06-20
• Study First Submitted QC: 2017-06-22
• Study First Posted: 2017-06-23
• Status Verified: 2018-03
• Primary Completion: 2018-05-30
• Study Completion: 2018-06-06
• Last Update Submitted: 2018-06-07
• Last Update Posted: 2018-06-08

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 12

Inclusion Criteria

• Patients with upper extremity dysfunction due to brain disorders (eg, stroke, traumatic brain injury, brain tumor, etc.)
• Patient who can move the upper limb against the gravity (MRC grade 3 or above in both shoulder and elbow flexion)
• Patient who can maintain stable sitting position
• Adults over 18 years old
• Patients who voluntarily agreed to participate in the study

Exclusion Criteria

• A moderate-to-severe cognitive impairment score of 18 or less in Mini-Mental Status Examination (MMSE)
• Peripheral nerve injury, joint disease, other diseases of the upper extremity dysfunctions other than brain disorders
• Patients with a history of severe dizziness or epilepsy
• Patients with other medical illness that are difficult to participate in the study

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: SINGLE_GROUP

Arm && Interventions

Group	Intervention	Description
Virtual rehabilitation	Virtual rehabilitation	Upper limb rehabilitation using virtual reality with a head-mounted display (HTC Vive; HTC Co., New Taipei City, Taiwan)

Primary Outcome Measures

Name	Time	Method
Change of Action Research Arm Test	at study completion, an average of 1 month	19 items including grasp, grip, pinch, and gross arm movement

Secondary Outcome Measures

Name	Time	Method
Change of Box and Block Test	at study completion, an average of 1 month	the number of blocks carried over the partition from one compartment to the other during the one-minute trial period
Change of Modified Barthel Index	at study completion, an average of 1 month	Evaluation of activities of daily living
Time of participation	at study completion, an average of 1 month	Total time of patient's participation in the study intervention
Patient's satisfaction	at study completion, an average of 1 month	Evaluation of patient's satisfaction to the study intervention using a Likert scale
Patient's discomfort	at study completion, an average of 1 month	Evaluation of patient's discomfort to the study intervention using a Likert

Trial Locations

Locations (2)

Seoul National University Hospital; 🇰🇷 Seoul, Korea, Republic of

Korea Workers' Compensation & Welfare Service Incheon Hospital; 🇰🇷 Incheon, Korea, Republic of