In vivo plaque calcium phosphate deposition from toothpaste
Not Applicable
- Conditions
- Dental cariesPlaque calcium phosphate mineral dynamicsOral and Gastrointestinal - Normal oral and gastrointestinal development and function
- Registration Number
- ACTRN12610000317099
- Lead Sponsor
- niversity of Otago
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- ot yet recruiting
- Sex
- All
- Target Recruitment
- 50
Inclusion Criteria
Radiation Therapy and Medical Students at the University of Otago Wellington
Exclusion Criteria
Requirement to treat for periodontal disease or other immediate dental treatment needed.
History of rheumatic heart disease/fever
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Increased calcium phosphate deposition in plaque assessed by measuring levels of calcium, phosphate, fluoride and protein in the dental plaque.[Initial assessment of the primary outcome parameters will be at baseline, then reassessed at week 4 after the 4 week standardisation period, and then again at week 8 following 4 week treatment with the plaque mineralising toothpaste.]
- Secondary Outcome Measures
Name Time Method
Related Research Topics
Explore scientific publications, clinical data analysis, treatment approaches, and expert-compiled information related to the mechanisms and outcomes of this trial. Click any topic for comprehensive research insights.
How does calcium phosphate in the novel toothpaste (ACTRN12610000317099) influence plaque mineralization and caries prevention mechanisms?
What is the comparative effectiveness of calcium phosphate toothpaste versus standard fluoride-based toothpastes in caries prevention?
Which biomarkers in dental plaque predict response to calcium phosphate mineralization in the ACTRN12610000317099 trial?
What potential adverse events are associated with calcium phosphate toothpaste in the ACTRN12610000317099 trial, and how are they managed?
What combination approaches with calcium phosphate toothpaste improve caries prevention in the ACTRN12610000317099 study?