Neuromuscular and Cognitive Fatigue During a 24h Treadmill Running Exercise.

Centre Hospitalier Universitaire de Saint Etienne1 site in 1 country30 target enrollmentSeptember 2007

ConditionsHealthy

Overview

Phase: Not Applicable
Intervention: Not specified
Conditions: Healthy
Sponsor: Centre Hospitalier Universitaire de Saint Etienne
Enrollment: 30
Locations: 1
Primary Endpoint: -Voluntary and electrically evoked forces on the contracted muscles
Status: Completed
Last Updated: 16 years ago

Overview Investigators Eligibility Criteria Outcomes Sites Similar Trials

Overview

Brief Summary

The main purpose of the present study is to determine the relative contributions of central and peripheral fatigue during an ultra-endurance exercise.

Detailed Description

For that purpose, 14 subjects running 24 hours on a treadmill will be compared with a control group being awake during the same period. Subjects who running will have electrically evoked forces on the muscles associated EMG activity, blood samples and muscle biopsy.

Registry

clinicaltrials.gov

Start Date

September 2007

End Date

December 2007

Last Updated

16 years ago

Study Type

Interventional

Study Design

Parallel

Sex

All

Investigators

Sponsor

Centre Hospitalier Universitaire de Saint Etienne

Eligibility Criteria

Inclusion Criteria

•The subjects of the experimental group will be recruited among experienced ultra-runners . They all have run at least a 12 hour race or longer.
•The control group will be recruited among experienced ultra-runners . Age of control group will be age experimental group more or less 2 years.

Exclusion Criteria

•The subjects will not be selected if:
•they were injured in the 3 months before the experiment
•they had a tendon or joint pathology that could impair strength measurements.
•they participate to an other experiment at the same time

Outcomes

Primary Outcomes

-Voluntary and electrically evoked forces on the contracted muscles

Time Frame: 24 hours

Secondary Outcomes

Electrically evoked forces on the relaxed muscles and associated EMG activity(24 hours)
Blood samples before the exercise(every 4 hours)
Muscle biopsy (vastus lateralis)(before and after the exercise)