Neuromuscular and Cognitive Fatigue During a 24 Hour Treadmill Running Exercise

Not Applicable

Completed

• Conditions: Healthy
• Interventions: Procedure: running during 24 hours without sleep; Other: no sleeping

• Registration Number: NCT00428779
• Lead Sponsor: Centre Hospitalier Universitaire de Saint Etienne

Brief Summary

The main purpose of the present study is to determine the relative contributions of central and peripheral fatigue during an ultra-endurance exercise.

Detailed Description

For that purpose, 14 subjects running 24 hours on a treadmill will be compared with a control group being awake during the same period. Subjects who running will have electrically evoked forces on the muscles associated EMG activity, blood samples and muscle biopsy.

Study Timeline

• Study First Submitted: 2007-01-29
• Study First Submitted QC: 2007-01-29
• Study First Posted: 2007-01-30
• Study Start: 2007-09
• Primary Completion: 2007-12
• Study Completion: 2007-12
• Status Verified: 2009-06
• Last Update Submitted: 2009-06-10
• Last Update Posted: 2009-06-11

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 30

Inclusion Criteria

• The subjects of the experimental group will be recruited among experienced ultra-runners . They all have run at least a 12 hour race or longer.
• The control group will be recruited among experienced ultra-runners . Age of control group will be age experimental group more or less 2 years.

Exclusion Criteria

• The subjects will not be selected if:

  • they were injured in the 3 months before the experiment
  • they had a tendon or joint pathology that could impair strength measurements.
  • they participate to an other experiment at the same time

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
1	running during 24 hours without sleep	patients running during 24 hours without sleep
2	no sleeping	patients without sleep during 24 hours

Primary Outcome Measures

Name	Time	Method
-Voluntary and electrically evoked forces on the contracted muscles	24 hours

Secondary Outcome Measures

Name	Time	Method
Muscle biopsy (vastus lateralis)	before and after the exercise
Electrically evoked forces on the relaxed muscles and associated EMG activity	24 hours
Blood samples before the exercise	every 4 hours

Trial Locations

Locations (1)

Pr André GEYSSANT; 🇫🇷 Saint-etienne, France