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Clinical Trials/NCT03850665
NCT03850665
Completed
N/A

Comparison of Early Objective and Subjective Outcome in Patients After Hip Arthroplasty, Operated From Direct Anterior, Posterolateraland Anterolateral Approach: Prospective Randomized Clinical Trial

Medical University of Warsaw2 sites in 1 country140 target enrollmentSeptember 27, 2020

Overview

Phase
N/A
Intervention
Not specified
Conditions
Hip
Sponsor
Medical University of Warsaw
Enrollment
140
Locations
2
Primary Endpoint
Change in biomechanical gait parameters
Status
Completed
Last Updated
4 years ago

Overview

Brief Summary

The aim of the study will be to compare functional outcomes of the two surgical hip approaches in total hip arthroplasty: anterior, posterolateral and anterolateral. Surgical approach may have influence on patients functional outcome.

Detailed Description

Patients with primary hip osteoarthritis will be included in a randomized controlled trial and assigned to total hip arthroplasty using one the of hip approaches: anterior or anterolateral. Subjects will be assessed preoperative and 3 and 12 moths postoperative. Biomechanical gait parameters will be collected using tree-dimensional motion analysis system "BTS SMART". Evaluation of the function of the middle gluteal muscle with superficial EMG (sEMG) percutaneous surface electromyography. Fatigue assessment (mean frequency and amplitude) of the gluteus medius muscle during isometric muscle contraction. Balance and coordination as well as fall risk will be assessed with use of dynamometric Biodex Balance platform. The study will determine the values of individual indicators: general stability index (OWS), anterior-posterior stability index (APW), the median lateral stability index (MLW) and the fall risk index (RU). Subjective assessment will be conducted with use of Visual Analogue Scale, WOMAC Index, Oxford Hip Score, The Short Form-36 (SF-36) and Harris Hip Score

Registry
clinicaltrials.gov
Start Date
September 27, 2020
End Date
October 1, 2021
Last Updated
4 years ago
Study Type
Interventional
Study Design
Parallel
Sex
All

Investigators

Sponsor
Medical University of Warsaw
Responsible Party
Principal Investigator
Principal Investigator

Artur Stolarczyk

Head of the Department of Orthopaedics and Rehabilitation, Principal Investigator, Clinical Professor

Medical University of Warsaw

Eligibility Criteria

Inclusion Criteria

  • patient's consent for anticipation in the study
  • BMI less than 35
  • ability to walk the distance of 10m and stand up from the chair
  • arthroplasty in one hip

Exclusion Criteria

  • patient's lack of consent for anticipation in the study
  • neurological diseases
  • balance disorders
  • reoperations in the area of endoprosthesis
  • muscles diseases
  • rheumatic diseases (rheumatoid arthritis, ankylosing spondylitis)
  • dizziness, vasovagal syncope

Outcomes

Primary Outcomes

Change in biomechanical gait parameters

Time Frame: from baseline (can be measured anytime to a maximum of one month before surgery) to 3 and 12 months post-operatively

Done by a biomechanics lab for patients to test their hip movements

Change from baseline in Hip disability and Osteoarthritis Outcome Score (HOOS) activities of daily living (ADL)

Time Frame: from baseline (can be measured anytime to a maximum of one month before surgery) to 3 and 12 months post-operatively

This asks the patient how their hip functions during their daily life. It has 5 subscales measuring Pain, Symptoms, ADL, Sports/Recreation and Quality of Life (which is calculated using all the subscores). Each subscale is calculated using the mean score, with each score range being from 0 to 4. The subscore is normalized such that the lower the number the more extreme the problem is. To calculate Quality of Life, the mean of the other 4 subscores are taken to calculate the score. This asks the patient how their hip functions during their daily life. It has 5 subscales measuring Pain, Symptoms, ADL, Sports/Recreation and Quality of Life (which is calculated using all the subscores). Each subscale is calculated using the mean score, with each score range being from 0 to 4. The subscore is normalized such that the lower the number the more extreme the problem is. To calculate Quality of Life, the mean of the other 4 subscores are taken to calculate the score.

Change in biomechanical coordination

Time Frame: from baseline (can be measured anytime to a maximum of one month before surgery) to 3 and 12 months post-operatively

Done by a biomechanics lab for patients to test their hip movements coordination

Change in biomechanical gait balance

Time Frame: from baseline (can be measured anytime to a maximum of one month before surgery) to 3 and 12 months post-operatively

Done by a biomechanics lab for patients to test their gait balance

Change in SF-36 scale

Time Frame: from baseline (can be measured anytime to a maximum of one month before surgery) to 3 and 12 months post-operatively

The SF-36 is a participant self-rated questionnaire that is a general measure of perceived health status comprising 36 questions, which yields an 8-scale health profile. The vitality sub-score assesses energy and fatigue, and ranges from 0 (worst) - 100 (best).

Change in Visual Analog Scale (VAS) scale

Time Frame: from baseline (can be measured anytime to a maximum of one month before surgery) to 3 and 12 months post-operatively

To measure pain. This is a line with left most end representing no pain with the rightmost representing extreme pain. The participant puts a line where they feel that day and it is measured with a ruler to determine score out of 100. The line is 100mm long.

Gluteus medius muscle fatigue

Time Frame: from baseline (can be measured anytime to a maximum of one month before surgery) to 3 and 12 months post-operatively

Surface Electromyographic analysis performed for testing gluteus medius activity

Change in Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC)

Time Frame: from baseline (can be measured anytime to a maximum of one month before surgery) to 3 and 12 months post-operatively

This measures health status as it relates to the hip. There are 3 subscales, pain which score ranges from 0-20, stiffness range from 0-8, physical function ranging from 0-68. The total score is just added up from the subscales.

Change in Oxford scale

Time Frame: from baseline (can be measured anytime to a maximum of one month before surgery) to 3 and 12 months post-operatively

The Oxford scale is a physiotherapist objective-rated scale to asses muscle strength against the resistance. It is graded from 0 (flicker of movement) to 5 (Through full range actively against strong resistance)

Secondary Outcomes

  • Radiological analysis of implants positioning(from baseline (can be measured anytime to a maximum of one month before surgery) to 3 and 12 months post-operatively)

Study Sites (2)

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