Combined Local Infiltration Analgesia and Femoral Nerve Blocks in Total Knee Replacements. A Prospective Randomised Controlled Trial

Phase 4

• Conditions: Osteoarthritis and other conditions leading to total knee replacement; Pain management following total knee replacement.; Anaesthesiology - Pain management; Musculoskeletal - Osteoarthritis; Surgery - Other surgery

• Registration Number: ACTRN12614000502639
• Lead Sponsor: ambour General Hospital

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2014-05-12
• Last Update Posted: 13 January 2020

Recruitment & Eligibility

• Status: ot yet recruiting
• Sex: All
• Target Recruitment: 90

Inclusion Criteria

i.Elective primary unilateral TKR performed at NGH
ii.Patients who consent to participate in the study
iii.Ability to comprehend pain scoring and ability to use PCA machine
iv.American Society of Anesthesiologists (ASA) Physical Status I-III
v.Patients aged 18-85 years

Exclusion Criteria

i.Patients who lack capacity, or are unwilling, to consent to the study
ii.Patients with pre-existing chronic pain syndromes
iii.Patients with opioid tolerance (opioid consumption >30mg oral morphine or equivalent per day)
iv.Chronic gabapentin or pregabalin analgesic therapy
v.Patients with known contraindication, allergy, intolerance or previous reaction to any of the drugs being administered
vi.Inability to walk independently prior to TKR
vii.Body Mass Index (BMI) >40 kg/m2
viii.Patients <18 years of age
ix.Patients who are pregnant
x.Patients who have dementia

Study & Design

• Study Type: Interventional
• Study Design: Not specified