CATCH - CATheter Infections in CHildre
- Conditions
- Children in Paediatric Intensive CareNot Applicable
- Registration Number
- ISRCTN34884569
- Lead Sponsor
- Institute of Child Health (UK)
- Brief Summary
2016 results in: http://www.ncbi.nlm.nih.gov/pubmed/26946925 2019 post-hoc analysis of thrombosis risk in: https://www.ncbi.nlm.nih.gov/pubmed/30921401 (added 18/12/2019)
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- All
- Target Recruitment
- 1200
1. Less than 16 years of age
2. Admitted to or being prepared for admission to an intensive care unit participating in the trial
3. Requires insertion of a central venous catheter
4. Requires one of the central venous catheter sizes available to the trial
5. Expected to require a central venous catheter for at least 3 days
1. Previously enrolled in the CATCH trial
2. Has a known allergy or hypersensitivity to tetracyclines (including minocycline), rifampicin or heparin?
3. Patient known to be pregnant
4. Patient known to have a history of heparin induced thrombocytopenia
5. Patient is in a randomised controlled trial that excludes participation in CATCH
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Time to first blood stream infection defined by a positive blood culture from a sample that was clinically indicated and taken more than 48 hours after CVC insertion and up to 48 hours after CVC removal
- Secondary Outcome Measures
Name Time Method