Skip to main content
MedPathMedPath Home
Clinical Trials/ISRCTN34884569
ISRCTN34884569
Completed
未知

A randomised controlled trial comparing the effectiveness of heparin bonded or antibiotic impregnated central venous catheters (CVCs) with standard CVCs for the prevention of hospital acquired blood stream infection in children

Institute of Child Health (UK)0 sites1,200 target enrollmentAugust 12, 2010
Share to TwitterShare to FacebookShare to LinkedInShare to Reddit
ConditionsChildren in Paediatric Intensive CareNot Applicable

Overview

Phase
未知
Intervention
Not specified
Conditions
Children in Paediatric Intensive Care
Sponsor
Institute of Child Health (UK)
Enrollment
1200
Status
Completed
Last Updated
6 years ago
OverviewInvestigatorsEligibility CriteriaOutcomesSimilar Trials

Overview

Brief Summary

2016 results in: http://www.ncbi.nlm.nih.gov/pubmed/26946925 2019 post-hoc analysis of thrombosis risk in: https://www.ncbi.nlm.nih.gov/pubmed/30921401 (added 18/12/2019)

Registry
who.int
Start Date
August 12, 2010
End Date
March 1, 2013
Last Updated
6 years ago
Study Type
Interventional
Sex
All

Investigators

Sponsor
Institute of Child Health (UK)

Eligibility Criteria

Inclusion Criteria

  • •1\. Less than 16 years of age
  • •2\. Admitted to or being prepared for admission to an intensive care unit participating in the trial
  • •3\. Requires insertion of a central venous catheter
  • •4\. Requires one of the central venous catheter sizes available to the trial
  • •5\. Expected to require a central venous catheter for at least 3 days

Exclusion Criteria

  • •1\. Previously enrolled in the CATCH trial
  • •2\. Has a known allergy or hypersensitivity to tetracyclines (including minocycline), rifampicin or heparin?
  • •3\. Patient known to be pregnant
  • •4\. Patient known to have a history of heparin induced thrombocytopenia
  • •5\. Patient is in a randomised controlled trial that excludes participation in CATCH

Outcomes

Primary Outcomes

Not specified

Similar Trials

Completed
Not Applicable
Pilot randomised trial comparing the effect of different strengths of an antiseptic solution, chlorhexidine gluconate, on central venous catheter related infections in haemodialysis patients in three outpatient haemodialysis centres
ISRCTN26577745Trinity College Dublin (Ireland)180
Completed
Not Applicable
A randomized clinical trial comparing the effectiveness of rotator cuff repair with or without augmentation with porcine small intestine submucosa (SIS) for large rotator cuff tears: Pilot study phaseRotator cuff tearsMusculoskeletal DiseasesLarge rotator cuff tears
ISRCTN73698035McMaster University (Canada)62
Completed
Not Applicable
The role and effect of limited formula use on breastfeeding and its discontinuatioBreastfeedingNot Applicable
ISRCTN61915183Institute for the Care of Mother and Child100
Completed
Not Applicable
REducing Stress and Preventing Depression (RESPOND)Major Depressive DisorderGeneralised Anxiety DisorderMental and Behavioural Disorders
ISRCTN12683436niversity of Exeter (UK)235
Completed
Not Applicable
A randomised controlled trial of the efficacy and cost-effectiveness of a very brief intervention to increase physical activity when delivered in a primary care settingTopic: Primary CareSubtopic: Not AssignedDisease: All DiseasesNot Applicable
ISRCTN72691150niversity of Cambridge (UK)1,007