ISRCTN34884569Completed未知
A randomised controlled trial comparing the effectiveness of heparin bonded or antibiotic impregnated central venous catheters (CVCs) with standard CVCs for the prevention of hospital acquired blood stream infection in children
Institute of Child Health (UK)0 sites1,200 target enrollmentStarted: August 12, 2010Last updated:
Conditions
Trial Snapshot
- Phase
- 未知
- Status
- Completed
- Sponsor
- Enrollment
- 1,200
Study Overview
Brief Summary
2016 results in: http://www.ncbi.nlm.nih.gov/pubmed/26946925 2019 post-hoc analysis of thrombosis risk in: https://www.ncbi.nlm.nih.gov/pubmed/30921401 (added 18/12/2019)
Study Design
- Study Type
- Interventional
Eligibility Criteria
- Sex
- All
Inclusion Criteria
- •1. Less than 16 years of age
- •2. Admitted to or being prepared for admission to an intensive care unit participating in the trial
- •3. Requires insertion of a central venous catheter
- •4. Requires one of the central venous catheter sizes available to the trial
- •5. Expected to require a central venous catheter for at least 3 days
Exclusion Criteria
- •1. Previously enrolled in the CATCH trial
- •2. Has a known allergy or hypersensitivity to tetracyclines (including minocycline), rifampicin or heparin?
- •3. Patient known to be pregnant
- •4. Patient known to have a history of heparin induced thrombocytopenia
- •5. Patient is in a randomised controlled trial that excludes participation in CATCH
Investigators
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