Advanced Medical Imaging in Subpatent Malaria: a pilot study

Not Applicable

Completed

• Conditions: Parasite sequestration in experimental subpatent malaria infection induced by the induced blood stage malaria human challenge model.; Infection - Other infectious diseases

• Registration Number: ACTRN12616001238460
• Lead Sponsor: QIMR-Berghofer Medical Research Institute

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2016-09-06
• Study Completion: 2017-04-13
• Last Update Posted: 17 February 2020

Recruitment & Eligibility

• Status: Completed
• Sex: All
• Target Recruitment: 3

Inclusion Criteria

*Provide signed and dated informed consent form
*Able to lie supine and still for duration of image acquisition
*Participating in induced blood stage malaria human challenge model study

Exclusion Criteria

*Known allergic reactions to components of the study radiotracer 18F FDG
*Fasted blood glucose elevated above the normal range (BSL >6.0mmol/L)
*Failure to meet/provide the standard MRI checklist requirements
*Claustrophobia precluding image acquisition
*Significant previous radiation exposure as defined (lifetime exposure):
a. Any fluoroscopic imaging (e.g. coronary angiography)
b. Any nuclear medicine imaging (e.g. myocardial perfusion scan)
c Greater than one previous CT scan
d. Note: previous plain film X-rays and mammography are acceptable

Study & Design

• Study Type: Observational
• Study Design: Not specified