Painful Knee Prosthesis. Relationship Between Endogenous Analgesia and Persistent Post Surgical Pain.
Overview
- Phase
- N/A
- Intervention
- Not specified
- Conditions
- Knee Osteoarthritis
- Sponsor
- Parc de Salut Mar
- Enrollment
- 180
- Locations
- 1
- Primary Endpoint
- Presence of pain in the operated knee, 6 months after surgery.
- Status
- Completed
- Last Updated
- 10 years ago
Overview
Brief Summary
This is a prospective, observational study, aimed to establish the relationship between an inefficient endogenous pain modulation before surgery (total knee arthroplasty; TKA) and the probability to develop chronic pain after surgery (persistent post surgical pain). Endogenous analgesia efficiency will be measured during the month previous to surgery using quantitative sensory testing (QST). Persistent post surgical pain will be defined as presence of pain in movement greater than 3 points in a 0-10 numerical scale in the operated knee, 6 months after surgery.
Investigators
CDursteler
MD
Parc de Salut Mar
Eligibility Criteria
Inclusion Criteria
- •Older than 18 patients
- •Scheduled for primary total knee arthroplasty
- •Disposition to visits and scheduled tests
Exclusion Criteria
- •Previous surgery on knee to be operated
- •Documented peripheral neuropathy
- •Severe disease or condition that could potentially interfere with interpretation of tests.
Outcomes
Primary Outcomes
Presence of pain in the operated knee, 6 months after surgery.
Time Frame: Presence of pain greater than 3 points in a 0-10 numerical scale in the operated knee, 6 months after surgery.
Secondary Outcomes
- Endogenous Analgesia efficiency measured with QST (Quantitative sensory testing) techniques.(From start of recruitment untill day 180.)