Painful Knee Prosthesis. Relationship Between Endogenous Analgesia and Persistent Post Surgical Pain.
Completed
- Conditions
- Knee Osteoarthritis
- Interventions
- Behavioral: Quantitative sensory testing (QST)
- Registration Number
- NCT01811888
- Lead Sponsor
- Parc de Salut Mar
- Brief Summary
This is a prospective, observational study, aimed to establish the relationship between an inefficient endogenous pain modulation before surgery (total knee arthroplasty; TKA) and the probability to develop chronic pain after surgery (persistent post surgical pain). Endogenous analgesia efficiency will be measured during the month previous to surgery using quantitative sensory testing (QST). Persistent post surgical pain will be defined as presence of pain in movement greater than 3 points in a 0-10 numerical scale in the operated knee, 6 months after surgery.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- All
- Target Recruitment
- 180
Inclusion Criteria
- Older than 18 patients
- Scheduled for primary total knee arthroplasty
- Disposition to visits and scheduled tests
Exclusion Criteria
- Previous surgery on knee to be operated
- Documented peripheral neuropathy
- Severe disease or condition that could potentially interfere with interpretation of tests.
Study & Design
- Study Type
- OBSERVATIONAL
- Study Design
- Not specified
- Arm && Interventions
Group Intervention Description Patients with knee osteoarthritis Quantitative sensory testing (QST) -
- Primary Outcome Measures
Name Time Method Presence of pain in the operated knee, 6 months after surgery. Presence of pain greater than 3 points in a 0-10 numerical scale in the operated knee, 6 months after surgery.
- Secondary Outcome Measures
Name Time Method Endogenous Analgesia efficiency measured with QST (Quantitative sensory testing) techniques. From start of recruitment untill day 180.
Trial Locations
- Locations (1)
Servicio d'Anestesia i Reanimació, Hospital del Mar
🇪🇸Barcelona, Spain