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Effect of Prompting the Supply of Zinc/LO-ORS Co-packs in the Private Sector Plus BCI on Childhood Diarrhea Treatment

Not Applicable
Completed
Conditions
Diarrhea, Infantile
Interventions
Other: Private sector component + modified BCC
Registration Number
NCT04335877
Lead Sponsor
Nutrition International
Brief Summary

This study assesses whether prompting the supply of zinc and LO-ORS co-packs in the private sector coupled with behavior change communication (BCC) has an effect on the treatment of uncomplicated childhood diarrhea. In addition the study will evaluate the acceptability, adoption, feasibility and coverage of the intervention model. One group of children and caregivers will receive the current standard of care and will be exposed to standard BCC and the second group will be exposed to the private sector component and to a modified BCC.

Detailed Description

Diarrhoea accounts for 7% of all under-five deaths in Kenya. Recent experiences in other countries show that the private health sector can be successfully harnessed to improve diarrhoea treatment coverage.

This study assesses the effect of prompting the supply of zinc and low-osmolarity oral rehydration salts (LO-ORS) co-packs in the private sector coupled with increasing the demand for co-packs among caregivers on: 1) the treatment of uncomplicated childhood diarrhoea, 2) care-seeking in the private sector, and 3) availability of co-packs in the private sector.

The target population will be children under five years of age and their caregivers in Vihiga County. The study will use a effectiveness-implementation hybrid design with two arms: 1) children and caregivers from areas that receive the current standard of care and will be exposed to standard BCC and 2) children and caregivers from areas where the private sector component will be implemented and that will be exposed to a modified BCC. Two of the five existing sub-counties in Vihiga will be selected by convenience to be assigned to one of the two study arms. The selection will take into account geographical distance between the two sub-counties (i.e. maximizing the distance between the two counties to minimize cross-pollination between the two study groups), rural vs urban population, and number of operational community units and CHV in each sub-county. All private sector retailers within each sub-county will be identified with assistance from wholesalers. Retailers will be invited to participate in the study via sensitization meetings.

Baseline and endline assessments will be conducted at the household level to collect information on care-seeking practices, availability of the co-pack in the household, treatment of diarrhoea, and whether caregivers received information from shopkeepers on using the co-pack. Monitoring of process indicators will be conducted throughout the intervention period. The monitoring process will also be used to evaluate the adoption and feasibility of the implementation model. In addition, the endline survey will be used to evaluate the acceptability, adoption, and coverage of the implementation model.

Recruitment & Eligibility

Status
COMPLETED
Sex
All
Target Recruitment
1245
Inclusion Criteria

Not provided

Exclusion Criteria

Not provided

Study & Design

Study Type
INTERVENTIONAL
Study Design
PARALLEL
Arm && Interventions
GroupInterventionDescription
Private sector component + modified BCCPrivate sector component + modified BCCPrivate sector component + modified BCC + current standard of care
Primary Outcome Measures
NameTimeMethod
Adoption by private sector at month 22 months

% private retailers who stock co-pack after 2 months

Care-seeking in the private sector12 months

Change in % of caregivers seek care for uncomplicated childhood diarrhea in the private sector at 12 months

Adoption by private sector at month 44 months

% private retailers who stock co-pack after 4 months

Availability of zinc and LO-ORS co-pack in the private sector12 months

Change in % of private retailers who have stock of zinc and LO-ORS co-pack at time of visit at 12 months

Treatment of uncomplicated diarrhea12 months

change in % of caregivers who use zinc and LO-ORS co-pack to treat uncomplicated childhood diarrhea at 12 months

Acceptability of private sector1 month

% private retailers who express intention to stock co-packs after sensitization and training.

Acceptability of caregivers12 months

% caregivers who indicate preferred treatment for uncomplicated childhood diarrhea is co-pack.at 12 months

Adoption by private sector at month 11 month

% private retailers who stock co-pack after 1 month

Adoption by private sector at month 66 months

% private retailers who stock co-pack after 6 months

Adoption by private sector at month 77 months

% private retailers who stock co-pack after 7 months

Adoption by private sector at month 88 months

% private retailers who stock co-pack after 8 months

Adoption by private sector at month 33 months

% private retailers who stock co-pack after 3 months

Adoption by private sector at month 1212 months

% private retailers who stock co-pack after 12 months

Feasibility of intervention at month 88 months

% private retailers who indicate that they can purchase/procure co-packs with ease after 8 months

Feasibility of intervention at month 99 months

% private retailers who indicate that they can purchase/procure co-packs with ease after 9 months

Adoption by private sector at month 99 months

% private retailers who stock co-pack after 9 months

Adoption by caregivers12 months

% caregivers who indicate having co-pack in house

Feasibility of intervention at month 11 month

% private retailers who indicate that they can purchase/procure co-packs with ease after 1 month

Feasibility of intervention at month 44 months

% private retailers who indicate that they can purchase/procure co-packs with ease after 4 months

Feasibility of intervention at month 1111 months

% private retailers who indicate that they can purchase/procure co-packs with ease after 11 months

Adoption by private sector at month 55 months

% private retailers who stock co-pack after 5 months

Adoption by private sector at month 1111 months

% private retailers who stock co-pack after 11 months

Feasibility of intervention at month 66 months

% private retailers who indicate that they can purchase/procure co-packs with ease after 6 months

Adoption by private sector at month 1010 months

% private retailers who stock co-pack after 10 months

Feasibility of intervention at month 55 months

% private retailers who indicate that they can purchase/procure co-packs with ease after 5 months

Feasibility of intervention at month 22 months

% private retailers who indicate that they can purchase/procure co-packs with ease after 2 months

Feasibility of intervention at month 33 months

% private retailers who indicate that they can purchase/procure co-packs with ease after 3 months

Feasibility of intervention at month 77 months

% private retailers who indicate that they can purchase/procure co-packs with ease after 7 months

Feasibility of intervention at month 1010 months

% private retailers who indicate that they can purchase/procure co-packs with ease after 10 months

Feasibility of intervention at month 1212 months

% private retailers who indicate that they can purchase/procure co-packs with ease after 12 months

Secondary Outcome Measures
NameTimeMethod
Care-seeking to all sources12 months

Change in % of caregivers who seek care for childhood diarrhea outside the home at month 12

Caregivers receive information from private retailers12 months

Change in % caregivers who indicate received information from private retailers about zinc and LO-ORS to treat uncomplicated childhood diarrhea at 12 months

Prompt treatment of uncomplicated childhood diarrhoea with zinc and LO-ORS co-pack12 months

Change in % of caregivers who use zinc and LO-ORS co-pack to treat uncomplicated childhood diarrhea within 24-h of the onset of the episode of diarrhea at 12 months

Trial Locations

Locations (1)

Nutrition International - Kenya

🇰🇪

Nairobi, Kenya

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