A study of therapeutic effect of blood ozone therapy of severe Covid-19 patients

Not Applicable

Recruiting

• Conditions: Covid-19.; virus identified, Clinically-epidemiologically diagnosed COVID-19; U07.1

• Registration Number: IRCT20200616047792N1
• Lead Sponsor: Ahvaz University of Medical Sciences

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Last Update Posted: 7 September 2020

Recruitment & Eligibility

• Status: Recruiting
• Sex: All
• Target Recruitment: 60

Inclusion Criteria

Severe cases of Covid-19 with chest CT changes in the form of peripheral uni- or bilateral ground glass opacity(s) in combination with any of the below: RR greater than 24, O2 Sat less than 93%, BP less than 90/60, decreased level of consciousness.

Exclusion Criteria

G6PD Deficiency
Coagulopathies and thrombocytopenia
Hx of seizure
Hypothyroidism
Pancreatitis
Hemophilias
Acute alcohol poisoning
Pregnancy and breast feeding
Allergy to ozone and ozonated products

Study & Design

• Study Type: interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
ength of hospital stay. Timepoint: Daily since the time of hospitalization. Method of measurement: patient's file.

Secondary Outcome Measures

Name	Time	Method
eed for ICU. Timepoint: Daily since hospitalization. Method of measurement: Patient's file.;Duration of ICU stay. Timepoint: Daily since ICU stay. Method of measurement: Patient's file.;Need for mechanical ventilation. Timepoint: Daily since hospitalization. Method of measurement: Patient's file.;Duration of need for mechanical ventilation. Timepoint: Daily since mechanical ventilation. Method of measurement: Patient's file.;Case fatality rate. Timepoint: Daily since intervention. Method of measurement: Patient's file.;C-reactive protein. Timepoint: Thrice weekly. Method of measurement: Biochemistry method.;White blood cell count. Timepoint: Thrice weekly. Method of measurement: Cell counter.;Change in lung CT scan appearance. Timepoint: End of week one and week two. Method of measurement: Chest spiral CT scan.;ESR. Timepoint: Thrice weekly. Method of measurement: Biochemistry method.