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临床试验/ISRCTN72275160
ISRCTN72275160进行中(未招募)4 期

Proactive against reactive therapy for the prevention of lichen sclerosus exacerbation and progression of disease – a pragmatic, parallel group randomised controlled trial with embedded economic evaluation and process evaluation

ottingham Clinical Trials Unit0 个研究点目标入组 400 人开始时间: 2024年3月8日最近更新:
适应症

试验速览

阶段
4 期
状态
进行中(未招募)
发起方
入组人数
400

研究概览

简要总结

暂无简介。

研究设计

研究类型
Interventional

入排标准

性别
Female

入选标准

  • 1. Clinical or biopsy confirmed diagnosis of vulval LS
  • 2. Currently controlled disease (asymptomatic with minimal clinical evidence of active disease) at baseline
  • 3. Age =5 years
  • 4. Able to give consent/child assent plus parental consent

排除标准

  • 1. Previous vulval intraepithelial neoplasia (VIN) or vulval squamous cell carcinoma (SCC)
  • 2. Contraindications to topical steroids
  • 3. Concomitant use of other topical anti-inflammatory vulval treatments
  • 4. Using systemic immunosuppressants (for any indication)
  • 5. Using systemic treatment for LS
  • 6. Patients with surgical alteration of vulval skin as part of gender reaffirming surgery, or patients not born with a vulva
  • 7. Pregnant and breastfeeding women

研究者

发起方
ottingham Clinical Trials Unit

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