A study comparing the effects of two different doses of intravenous Dexmedetomidine (0.5 mcg/kg and 1 mcg/kg) on changes in heart rate and blood pressure during removal of endotracheal tube in abdominal surgeries.
Phase 2
- Conditions
- Health Condition 1: O- Medical and Surgical
- Registration Number
- CTRI/2024/04/065697
- Lead Sponsor
- Dr Shubhra Paul
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- ot Yet Recruiting
- Sex
- Not specified
- Target Recruitment
- 0
Inclusion Criteria
1.18 -45 years in both sex.
2.ASA grade I and II
3.Elective Abdominal Surgeries
Exclusion Criteria
1.Active upper respiratory tract infections.
2.Known case of drug allergy.
3 Patients with respiratory dysfunction and obstructive sleep apnea.
4.Patients who are obese.
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method To determine whether Dexmedetomidine 0.5 microgram per kilogram body weight or Dexmedetomidine 1 microgram per kilogram body weight is more effective in attenuating haemodynamic responses like heart rate, mean arterial pressure,systolic blood pressure and diastolic blood pressure during extubation in abdominal surgeries.Timepoint: Outcomes mentioned above will be measured at 0 mins, 1 min, 3 mins, 5 mins, 10 mins, 15 mins, 20 mins, 25 mins and 30 mins.
- Secondary Outcome Measures
Name Time Method To compare the effects of Dexmedetomidine 0.5 mcg/kg ,1 mcg/kg and placebo on extubation quality score.Timepoint: To assess the extubation quality score between all the groups from extubation to every 5 mins up to 30 mins after extubation.