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Study the Safety and Effectiveness of Tadalafil in Men With Problems Getting or Maintaining an Erection When Taken Prior to Desiring an Erection

Phase 3
Completed
Conditions
Impotence
Interventions
Drug: placebo
Registration Number
NCT00547495
Lead Sponsor
Eli Lilly and Company
Brief Summary

Study to determine how safe and effective tadalafil is for Japanese men taking it when they need to get and keep an erection.

Detailed Description

Not available

Recruitment & Eligibility

Status
COMPLETED
Sex
Male
Target Recruitment
343
Inclusion Criteria
  • 3 months history of erectile dysfunction (ED)
  • Anticipate a monogamous relationship with a female sexual partner
  • Be able to make minimum required sexual intercourse attempts
  • Abstain from using any other ED treatment
Exclusion Criteria
  • Other primary sexual disorders
  • History of radical prostatectomy or other pelvic surgery that affected being able to have an erection
  • History of penile implant or clinically significant penile deformity.
  • Nitrate use
  • Certain heart problems

Study & Design

Study Type
INTERVENTIONAL
Study Design
PARALLEL
Arm && Interventions
GroupInterventionDescription
1placeboPlacebo tablet
2tadalafil5 mg tadalafil
4tadalafil20 mg tadalafil
3tadalafil10 mg tadalafil
Primary Outcome Measures
NameTimeMethod
Effectiveness measured by IIEF score of questions 1-5 and 15 plus the percentages of positive responses to questions 2 and 3 in SEP diary12 weeks
Secondary Outcome Measures
NameTimeMethod
Change from baseline to endpoint of various questions from the IIEF and SEP diary12 weeks

Trial Locations

Locations (1)

For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Mon- Fri from 9 AM to 5 PM Eastern Time (UTC/GMT - 5 hours, EST), or speak with your personal physician.

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Sapporo, Hokkaido, Japan

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