Effects of cow*s milk consumption on estrogen levels in human male volunteers

Completed

• Conditions: humane blootstelling aan estrogenen via melkconsumptie; niet van toepassing

• Registration Number: NL-OMON34786
• Lead Sponsor: niversiteit Utrecht

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Last Update Posted: 2024-08-12

Recruitment & Eligibility

• Status: Completed
• Sex: Not specified
• Target Recruitment: 20

Inclusion Criteria

Volunteers (20) will be recruited at the campus of Utrecht University (de Uithof, living within 30 min travel). Healthy young males (20-23 year-old) are selected to reduce the possibility of confounding (see also exclusion criteria). A person is regarded healthy if they have none of the health problems described under exclusion criteria. Only Dutch Caucasian males are selected because of their likely encounter with dairy products, limiting the risk of health problems due to milk allergies or lactose intolerance during the study. Males are chosen for their low estrogen levels, making it possible to measure subtle concentration changes in urine. In addition, participants should have an adequate command of Dutch in order to avoid language problems with filling out questionnaires.

Exclusion Criteria

Volunteers that have dairy intolerance or allergies are excluded to avoid health problems due to the nature of the study. Potential volunteers with a deficiency in liver metabolism or hormonal afflictions are excluded from this research to avoid confounding of the results on urinary hormone levels. Vegetarians are excluded from this study because of a possible high dietary intake of phytoestrogens. Smokers are excluded in view of induction of cytochrome P450 enzymes. Participation in other medical-scientific investigations could result in confounding in all involved studies. Women are excluded because of monthly menstrual-cycle related variations in systemic estrogen levels and children are excluded because of ethical reasons.

Study & Design

• Study Type: Interventional
• Study Design: Not specified