NL-OMON34786已完成不适用
Effects of cow*s milk consumption on estrogen levels in human male volunteers - Estrogen intake via cow*s milk
适应症
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 20
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Interventional
入排标准
- 年龄范围
- 18 至 99（—）
入选标准
- •Volunteers (20) will be recruited at the campus of Utrecht University (de Uithof, living within 30 min travel). Healthy young males (20-23 year-old) are selected to reduce the possibility of confounding (see also exclusion criteria). A person is regarded healthy if they have none of the health problems described under exclusion criteria. Only Dutch Caucasian males are selected because of their likely encounter with dairy products, limiting the risk of health problems due to milk allergies or lactose intolerance during the study. Males are chosen for their low estrogen levels, making it possible to measure subtle concentration changes in urine. In addition, participants should have an adequate command of Dutch in order to avoid language problems with filling out questionnaires.
排除标准
- •Volunteers that have dairy intolerance or allergies are excluded to avoid health problems due to the nature of the study. Potential volunteers with a deficiency in liver metabolism or hormonal afflictions are excluded from this research to avoid confounding of the results on urinary hormone levels. Vegetarians are excluded from this study because of a possible high dietary intake of phytoestrogens. Smokers are excluded in view of induction of cytochrome P450 enzymes. Participation in other medical-scientific investigations could result in confounding in all involved studies. Women are excluded because of monthly menstrual-cycle related variations in systemic estrogen levels and children are excluded because of ethical reasons.
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