Children With Diabetes at Risk for Heart Disease.
- Conditions
- Diabetes Mellitus, Type 1Diabetes Complications
- Registration Number
- NCT02275091
- Lead Sponsor
- Georgetown University
- Brief Summary
Patients with type 1 diabetes type 1 (DM1) have increased risk of death due to heart disease and stroke. These cardiovascular conditions (CVD) are the leading cause of death in patients with DM1 younger than 40 years of age and up to 35% of all persons with DM1 will die before age 55 from CVD. Strategies are needed to help identify adolescents with DM1 at risk for CVD so that interventions to prevent heart disease and stroke can be undertaken.
- Detailed Description
Patients with type 1 diabetes and healthy controls will have evaluation of their lipid profile. Arterial stiffness, heart rate variability and adiposity measurements will be done in patients with type 1 diabetes and healthy controls. Blood pressure and heart rate will be recorded. 50 ml of urine will be collected from patients and controls.
All studies will be performed as a single outpatient visit at Georgetown University.
Recruitment & Eligibility
- Status
- UNKNOWN
- Sex
- All
- Target Recruitment
- 240
Diabetes type 1 or Healthy
Taking medications that lower cholesterol Duration of type 1 diabetes < 1 year.
Study & Design
- Study Type
- OBSERVATIONAL
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method small LDL particles This is an observational cross sectional study. Samples will be collected through study completion, on average of 6 years duration. Blood test, based on NMR
- Secondary Outcome Measures
Name Time Method
Trial Locations
- Locations (1)
Georgetown-Howard Universities Center
🇺🇸Washington, District of Columbia, United States