Remifentanil versus Fentanyl for pain control during elective endotracheal intubation in preterm neonates
- Conditions
- Respiratory distress syndrome of newborn.Hyaline membrane disease
- Registration Number
- IRCT201310164113N7
- Lead Sponsor
- Vice Chancellor for Research of Tabriz University of of Medical Sciences
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete
- Sex
- All
- Target Recruitment
- 32
Preterm newborns with gestational age between 28 to 34 weeks and 6 days from last menstrual period of mother who was born in Alzahra teaching hospital of Tabriz; clinical criteria of respiratory distress (consists of: tachypnea, grunting, inter coastal retraction and increased oxygen requirement) and radio graphic findings of Respiratory Distress Syndrome; need for surfactant treatment by INSURE (Intubate, Surfactant, Extubate) procedure.
Exclusion criteria: other causes of respiratory distress in newborns; second or third degree AV heart block; use of fentanyl during 4 hours from delivery; severe asphyxia (APGAR score under 5 at 5th minutes after delivery ); impaired consciousness level; major congenital anomalies; difficult intubation due to facial anomalies; more than three attempts for intubation.
Not provided
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Pain Score. Timepoint: During endotracheal intubation. Method of measurement: PIPP-R pain assessment tool (Premature Infant Pain Profile-Revised).
- Secondary Outcome Measures
Name Time Method