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EFFICACY OF ROUTINE MANAGEMENT BY LOCAL ANAESTHETIC INFILTRATION IN THE TREATMENT OF PUDENDAL NEURALGIA: A RANDOMISED TRIAL AGAINST SALINE

Phase 1
Conditions
Patients with pudendal neuralgia who have failed drug treatment
Therapeutic area: Analytical, Diagnostic and Therapeutic Techniques and Equipment [E] - Therapeutic techniques [E02]
Registration Number
EUCTR2021-001494-23-FR
Lead Sponsor
Groupe Hospitalier Diaconesses-Croix-Saint-Simon
Brief Summary

Not available

Detailed Description

Not available

Recruitment & Eligibility

Status
Authorised-recruitment may be ongoing or finished
Sex
All
Target Recruitment
60
Inclusion Criteria

Patient 18 years of age or older,
- Express consent to participate in the study
- Affiliated or beneficiary of a social security plan
- With pudendal neuralgia (modified Nantes criteria).
- MRI normal or without pathology explaining the pain
- Failure of drug treatment as defined in the NPs, i.e. failure (VAS decrease < 3) of at least one antiepileptic and one antidepressant whose dosages were brought to the maximum possible or in whom a side effect did not allow the dose to be increased to its maximum allowed.

Are the trial subjects under 18? no
Number of subjects for this age range:
F.1.2 Adults (18-64 years) yes
F.1.2.1 Number of subjects for this age range 30
F.1.3 Elderly (>=65 years) yes
F.1.3.1 Number of subjects for this age range 30

Exclusion Criteria

Patient benefiting from a legal protection measure
- Pregnant or breastfeeding woman
- General and/or local infection (fistulous or cutaneous suppuration of the anal margin) in progress
- Known neurological pathology that may explain the pain
- Psychiatric pathology requiring medical treatment
- Anticoagulants or haemostasis disorders
- Hypersensitivity to lidocaine hydrochloride, local anaesthetics
- Recurrent porphyrias

Study & Design

Study Type
Interventional clinical trial of medicinal product
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
Secondary Outcome Measures
NameTimeMethod
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