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临床试验/NCT07350447
NCT07350447
尚未招募
不适用

Predictors of Laparoscopy Conversion in the Treatment of Adhesive Small Bowel Obstruction

Almazov National Medical Research Centre0 个研究点目标入组 170 人开始时间: 2026年1月1日最近更新:

概览

阶段
不适用
状态
尚未招募
发起方
Almazov National Medical Research Centre
入组人数
170

概览

简要总结

The goal of this observational study is to reveal predictors of unsuccessfull laparoscopic intervention in adult patients with adhesive small bowel obstruction. The main question it aims to answer is: are there any strong predictors of laparoscopy conversion in patients with small bowel obstruction, caused by intraabdominal adhesions.

详细描述

Considering the undeniable advantages of laparoscopic interventions over laparotomic ones, the question of choosing a surgical approach in patients with acute adhesive intestinal obstruction can be reformulated as follows: in what situations is endovideosurgical intervention generally appropriate and feasible? A laparoscopic approach to severely distended bowel loops and widespread adhesions may increase the risk of serious complications. Indeed, some authors report intestinal injury in 6.3-26.9% of patients undergoing laparoscopic adhesiolysis for acute adhesive intestinal obstruction, which is statistically significantly higher than the same rate in patients operated on using a traditional approach. Therefore, a priority should be addressing the issue of adequately selecting patients who, based on a number of clinical indicators, are suitable for laparoscopic surgery or, at least, have no contraindications. While some parameters, such as acute cardiovascular or respiratory failure and pregnancy in the third trimester, can be defined as absolute contraindications to endovideosurgical access, a number of clinical and instrumental indicators are debatable. Despite the fact that this issue has been extensively covered in the literature, and the list of predictors of unsuccessful laparoscopic adhesiolysis is currently quite impressive, a standardized approach to access selection is lacking or is determined largely intuitively.

The aim of this work is to determine reliable anamnestic, clinical and instrumental signs that would indicate a high risk of conversion of the laparoscopic intervention in patients with acute adhesive intestinal obstruction.

The study is planned to be a multicenter, retrospective case-control study. Clinical data will be collected at four medical institutions in St. Petersburg. The medical records of patients who underwent emergency and urgent surgery for acute adhesive intestinal obstruction will be analyzed.

研究设计

研究类型
Observational
观察模型
Case Control
时间视角
Retrospective

入排标准

年龄范围
18 Years 至 —(Adult, Older Adult)
性别
All
接受健康志愿者

入选标准

  • patients underwent emergency and urgent surgery for acute adhesive intestinal obstruction
  • the surgery was performed laparoscopically
  • the surgery was initiated laparoscopically and completed via laparotomy

排除标准

  • acute adhesive intestinal obstruction in the hernial sac
  • pregnant in the third trimester
  • patients with severe cardiovascular or respiratory failure
  • patients with hemodynamic shock

研究者

发起方
Almazov National Medical Research Centre
申办方类型
Other
责任方
Principal Investigator
主要研究者

Kotkov Pavel

Assistant professor of the general surgery department

Almazov National Medical Research Centre

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