Clinical and Radiographic Outcomes of Alveolar Ridge Preservation for Implant-prosthetic Rehabilitation in a Hospital Setting: a Prospective Study
试验速览
- 阶段
- 不适用
- 状态
- 尚未招募
- 入组人数
- 50
- 试验地点
- 1
- 主要终点
- Volumetric analysis
研究概览
简要总结
Dental implants are considered a predictable rehabilitative option following tooth extraction or in cases of missing teeth. In some situations, the inevitable alveolar ridge resorption that occurs after extraction may make the placement of standard-diameter (>3.5 mm) or standard-length implants difficult or even impossible without advanced bone augmentation procedures. To counteract post-extraction volumetric bone contraction, alveolar ridge preservation can be performed, consisting of placing a bone graft within the socket walls immediately after tooth extraction. Although this procedure cannot completely prevent dimensional changes, it has been shown to significantly reduce both horizontal and vertical ridge resorption, as reported in the scientific literature. However, there is a lack of clinical and radiographic studies evaluating the outcomes of implant rehabilitation following alveolar ridge preservation with standard-dimension implants in a hospital-based setting.
研究设计
- 研究类型
- Observational
- 观察模型
- Case Only
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Patients requiring alveolar ridge preservation procedures prior to implant rehabilitation of edentulous sites;
- •Age > 18;
- •Achievement of FMPS and FMBS ≤ 15%;
- •Signed written informed consent to participate in the study.
排除标准
- •Uncontrolled diabetes or hypertension;
- •Uncontrolled periodontal disease;
- •Inability to perform consistent and continuous follow-up;
- •Pregnancy or breastfeeding;
- •Inability to provide written informed consent.
研究组 & 干预措施
Alveolar ridge preservation
Patients aged 18 years and older requiring tooth extraction followed by alveolar ridge preservation to enable implant surgery and prosthetic rehabilitation of edentulous sites.
结局指标
主要结局
Volumetric analysis
时间窗: From tooth extraction to 6 months of follow up.
The dimensional change of hard tissues following bone regenerative procedures will be assessed radiographically by measuring horizontal and vertical bone resorption through CBCT comparison in patients treated in a hospital-based setting.
次要结局
- Esthetic evaluation(From tooth extraction to 5 years of follow-up)
- Implant success rate(From tooth extraction to 5 years of follow up)
- Implant survival rate(From tooth extraction to 5 years follow up)
- Prosthesis success rate(From tooth extraction to 5 years of follow up)
- Prosthesis survival rate(From tooth extraction to 5 years of follow up)
- Patient-Reported Outcome Measures(From tooth extraction to 5 years of follow up)
- Diabetes(From tooth extraction to 5 years of follow up)
- Glycated hemoglobin level(From tooth extraction to 5 years of follow up)
- Complete Blood Count(From tooth extraaction to 5 years of follow up)
- Histologic analysis(From tooth extraction to 6 months of follow up)
- Correlation of medications relevant to bone/soft tissue metabolism with implant health(From tooth extraction to 5 years of follow up)
- Correlation between osteoporosis status and implant health(From tooth extraction to 5 years of follow up)
- Correlation between cardiovascular disease and implant health(From tooth extraction to 5 years of follow up)