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Clinical Trials/NCT06756984
NCT06756984
Not Yet Recruiting
N/A

A Prospective Cohort Study on the Long-Term Outcomes and Prognostic Factors of Different Surgical Techniques for the Treatment of Sacral Tarlov Cysts

Beijing Jishuitan Hospital0 sites150 target enrollmentMay 13, 2025

Overview

Phase
N/A
Intervention
Not specified
Conditions
Not specified
Sponsor
Beijing Jishuitan Hospital
Enrollment
150
Primary Endpoint
Pain Reduction Assessed by Visual Analog Scale (VAS)
Status
Not Yet Recruiting
Last Updated
11 months ago

Overview

Brief Summary

Brief Summary

The goal of this observational study is to evaluate the long-term outcomes of different surgical techniques for sacral Tarlov cysts in adult patients aged 18-75 years diagnosed with symptomatic sacral Tarlov cysts. The main questions it aims to answer are:

  • Does one surgical technique result in better pain relief (measured by VAS score) and functional recovery (measured by JOA score) compared to others?
  • How do different surgical techniques impact the long-term recurrence rate and complication rate?

Researchers will compare three surgical techniques:

  1. Partial cyst wall resection with nerve root sleeve plasty.
  2. Partial cyst wall resection with nerve root sleeve reinforcement and reconstruction.
  3. Autologous fat/muscle with fibrin glue microscopic cyst filling.

Participants will:

  • Undergo one of the three surgical procedures based on clinical indications.
  • Complete preoperative and postoperative assessments, including pain and functional scoring, as well as MRI evaluations at baseline and during follow-up.
  • Participate in a follow-up program for up to 2 years to monitor outcomes and recurrence.
Registry
clinicaltrials.gov
Start Date
May 13, 2025
End Date
December 31, 2026
Last Updated
11 months ago
Study Type
Observational
Sex
All

Investigators

Responsible Party
Principal Investigator
Principal Investigator

Liu longqi

MSc, Neurosurgeon, Department of Neurosurgery, Beijing Jishuitan Hospital

Beijing Jishuitan Hospital

Eligibility Criteria

Inclusion Criteria

  • Not provided

Exclusion Criteria

  • Not provided

Outcomes

Primary Outcomes

Pain Reduction Assessed by Visual Analog Scale (VAS)

Time Frame: Baseline, 1 month, 3 months, 6 months, 12 months and 24 months postoperatively

Neurological Function Improvement Assessed by Japanese Orthopedic Association (JOA) Score

Time Frame: Baseline, 1 month, 3 months, 6 months, 12 months and 24 months postoperatively

Secondary Outcomes

  • Recurrence Rate of Sacral Tarlov Cysts(12 months postoperatively and annually up to 2 years)

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