A Prospective Cohort Study on the Long-Term Outcomes and Prognostic Factors of Different Surgical Techniques for the Treatment of Sacral Tarlov Cysts
试验速览
- 阶段
- 不适用
- 状态
- 尚未招募
- 入组人数
- 150
- 主要终点
- Pain Reduction Assessed by Visual Analog Scale (VAS)
研究概览
简要总结
Brief Summary
The goal of this observational study is to evaluate the long-term outcomes of different surgical techniques for sacral Tarlov cysts in adult patients aged 18-75 years diagnosed with symptomatic sacral Tarlov cysts. The main questions it aims to answer are:
- Does one surgical technique result in better pain relief (measured by VAS score) and functional recovery (measured by JOA score) compared to others?
- How do different surgical techniques impact the long-term recurrence rate and complication rate?
Researchers will compare three surgical techniques:
- Partial cyst wall resection with nerve root sleeve plasty.
- Partial cyst wall resection with nerve root sleeve reinforcement and reconstruction.
- Autologous fat/muscle with fibrin glue microscopic cyst filling.
Participants will:
- Undergo one of the three surgical procedures based on clinical indications.
- Complete preoperative and postoperative assessments, including pain and functional scoring, as well as MRI evaluations at baseline and during follow-up.
- Participate in a follow-up program for up to 2 years to monitor outcomes and recurrence.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Years 至 75 Years(Adult, Older Adult)
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- 未提供
排除标准
- 未提供
结局指标
主要结局
Pain Reduction Assessed by Visual Analog Scale (VAS)
时间窗: Baseline, 1 month, 3 months, 6 months, 12 months and 24 months postoperatively
Neurological Function Improvement Assessed by Japanese Orthopedic Association (JOA) Score
时间窗: Baseline, 1 month, 3 months, 6 months, 12 months and 24 months postoperatively
次要结局
- Recurrence Rate of Sacral Tarlov Cysts(12 months postoperatively and annually up to 2 years)
研究者
Liu longqi
MSc, Neurosurgeon, Department of Neurosurgery, Beijing Jishuitan Hospital
Beijing Jishuitan Hospital
