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临床试验/NCT06756984
NCT06756984尚未招募不适用

A Prospective Cohort Study on the Long-Term Outcomes and Prognostic Factors of Different Surgical Techniques for the Treatment of Sacral Tarlov Cysts

Beijing Jishuitan Hospital0 个研究点目标入组 150 人开始时间: 2025年5月13日最近更新:

试验速览

阶段
不适用
状态
尚未招募
入组人数
150
主要终点
Pain Reduction Assessed by Visual Analog Scale (VAS)

研究概览

简要总结

Brief Summary

The goal of this observational study is to evaluate the long-term outcomes of different surgical techniques for sacral Tarlov cysts in adult patients aged 18-75 years diagnosed with symptomatic sacral Tarlov cysts. The main questions it aims to answer are:

  • Does one surgical technique result in better pain relief (measured by VAS score) and functional recovery (measured by JOA score) compared to others?
  • How do different surgical techniques impact the long-term recurrence rate and complication rate?

Researchers will compare three surgical techniques:

  1. Partial cyst wall resection with nerve root sleeve plasty.
  2. Partial cyst wall resection with nerve root sleeve reinforcement and reconstruction.
  3. Autologous fat/muscle with fibrin glue microscopic cyst filling.

Participants will:

  • Undergo one of the three surgical procedures based on clinical indications.
  • Complete preoperative and postoperative assessments, including pain and functional scoring, as well as MRI evaluations at baseline and during follow-up.
  • Participate in a follow-up program for up to 2 years to monitor outcomes and recurrence.

研究设计

研究类型
Observational
观察模型
Cohort
时间视角
Prospective

入排标准

年龄范围
18 Years 至 75 Years(Adult, Older Adult)
性别
All
接受健康志愿者

入选标准

  • 未提供

排除标准

  • 未提供

结局指标

主要结局

Pain Reduction Assessed by Visual Analog Scale (VAS)

时间窗: Baseline, 1 month, 3 months, 6 months, 12 months and 24 months postoperatively

Neurological Function Improvement Assessed by Japanese Orthopedic Association (JOA) Score

时间窗: Baseline, 1 month, 3 months, 6 months, 12 months and 24 months postoperatively

次要结局

  • Recurrence Rate of Sacral Tarlov Cysts(12 months postoperatively and annually up to 2 years)

研究者

申办方类型
Other
责任方
Principal Investigator
主要研究者

Liu longqi

MSc, Neurosurgeon, Department of Neurosurgery, Beijing Jishuitan Hospital

Beijing Jishuitan Hospital

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