Magnetic Nanoparticle Sperm Separation for Teratozoospermia Male and Women Older Than 35 Years

Not Applicable

Completed

• Conditions: Infertility
• Interventions: Other: Sperm preparation for ICSI

• Registration Number: NCT03666364
• Lead Sponsor: Ibn Sina Hospital

Brief Summary

Women over 35 years old are likely to suffer from impaired oocyte repair capacity. Teratozoospermia is a condition reflects morphological affection of sperm. These spermatozoa would add an extra burden on the oocyte after ICSI. Whether selecting mature sperm by magnetic nanoparticle protocol would provide a more competent sperm to a likely affected oocyte would improve ICSI outcomes is the question of this research.

Detailed Description

Not available

Study Timeline

• Study First Submitted: 2018-09-09
• Study First Submitted QC: 2018-09-09
• Study First Posted: 2018-09-11
• Study Start: 2018-09-17
• Primary Completion: 2019-09-20
• Study Completion: 2019-10-01
• Status Verified: 2019-11
• Last Update Submitted: 2019-11-14
• Last Update Posted: 2019-11-18

Recruitment & Eligibility

• Status: COMPLETED
• Sex: Female
• Target Recruitment: 1400

Inclusion Criteria

• women indicated for ICSI but with teratozoospermia

Exclusion Criteria

• Women not failing in this group

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
Magnetic nanoparticle selection for teratozoospermia	Sperm preparation for ICSI	-

Primary Outcome Measures

Name	Time	Method
Ongoing pregnancy rate	Twelve weeks of gestation

Secondary Outcome Measures

Name	Time	Method
Embryo development after ICSI	Six days of culture

Trial Locations

Locations (3)

Qena Fertility Center; 🇪🇬 Qena, Egypt

IbnSina IVF Center; 🇪🇬 Sohag, Egypt

Banon Assiut; 🇪🇬 Assiut, Egypt