MedPath

sipIT2: Improving Adherence to Fluid Intake Guidelines for Kidney Stone Prevention

Not Applicable
Active, not recruiting
Conditions
Urolithiasis
Interventions
Behavioral: sipIT
Registration Number
NCT05196113
Lead Sponsor
Penn State University
Brief Summary

The purpose of this study is to examine the feasibility of using sipIT tools (i.e., wrist-worn sensors, smart water bottles, mobile applications) to increase compliance with physician-recommended fluid consumption guidelines in participants with a history of urolithiasis.

Detailed Description

The study uses a randomized controlled trial design with a 12-month intervention period and outcome assessments at baseline, 1, 3, and 12 months. Participants will be randomly assigned to groups. Both groups will receive usual care which involves education about fluid intake guidelines and encouragement to adhere to those guidelines from a clinician. The intervention group will additionally receive the sipIT intervention comprising a semi-automated fluid intake tracking system and context-sensitive, just-in-time notifications reminding them to drink.

Recruitment & Eligibility

Status
ACTIVE_NOT_RECRUITING
Sex
All
Target Recruitment
216
Inclusion Criteria
  • previous diagnosis of symptomatic kidney stone in past 5 yrs
  • 24-hr urine volume ≤ 2.0 L/day,
  • age 18 or older,
  • own iOS or Android smartphone,
  • proficient in English language,
  • capable of providing informed consent, and
  • willing to use a Fitbit smartwatch, connected water bottle, and mobile app for the study every day for a year, and receive text messages reminder to drink.
Exclusion Criteria
  • previous diagnosis with cystine stone,
  • pregnant or planning to become pregnant in the next 12 months,
  • concurrently participating in another study involving fluid intake or diet,
  • plan to have surgery or relocate outside the area within the next year
  • co-morbidities that preclude high fluid intake, conditions with high fluid losses (e.g., congestive heart failure, bariatric surgery, GI tract ostomy, short gut syndrome, chronic diarrhea including patients with ulcerative colitis/Crohn's disease, hyponatremia), or conditions that preclude ability to collect 24-hour urine (severe urinary incontinence),
  • active medical treatments that would impair protocol compliance,
  • chronic use of lithium, or
  • psychiatric conditions impairing compliance with the study protocol.

Study & Design

Study Type
INTERVENTIONAL
Study Design
PARALLEL
Arm && Interventions
GroupInterventionDescription
sipITsipITParticipants receive education and a digital tool to monitor their fluid intake and remind them when they have lapsed in regular fluid intake.
Primary Outcome Measures
NameTimeMethod
24-hr urine volume3 months

Change in urine volume from baseline

Secondary Outcome Measures
NameTimeMethod
24-hr urine volume1 month and 12 months

Change in urine volume from baseline

Urine supersaturations1 month, 3 months, and 12 months

Change in supersaturations of common stone-forming salts from baseline to 1/3/12 months

Habit strength for fluid intake3 months, and 12 months

Change in habit by the 4-item Self-Report Behavioural Automaticity Index (Gardner, Abraham, Lally \& de Bruijn, 2012, Int J Beh Nutr Phys Act; baseline to 3/12 months). Responses will be averaged so scores range from 1 (strongly disagree) to 7 (strongly agree) with higher scores indicating stronger habits for fluid intake.

Past-week fluid intake3 months, and 12 months

Change in past-week volume of fluid intake from baseline to 3/12 months

Trial Locations

Locations (2)

Penn State Hershey Medical Center

🇺🇸

Hershey, Pennsylvania, United States

Pennsylvania State University

🇺🇸

University Park, Pennsylvania, United States

© Copyright 2025. All Rights Reserved by MedPath