Effects of Cardiorespiratory Rehabilitation on the Right Ventricle in Pulmonary Hypertension
Overview
- Phase
- Not Applicable
- Intervention
- Not specified
- Conditions
- Pulmonary Hypertension
- Sponsor
- Centre Hospitalier Universitaire de Nice
- Enrollment
- 12
- Locations
- 1
- Primary Endpoint
- Improvement of the subpulmonary ITS at effort >20% (presence of a right ventricular contractile reserve) defined by the improvement of the ITS or integral subpulmonary time-speed)
- Status
- Completed
- Last Updated
- 2 years ago
Overview
Brief Summary
Clinical improvement has been demonstrated after cardiorespiratory rehabilitation in patients with pulmonary hypertension. Rehabilitation is therefore now part of the recommendations for good practice. However, no data is available to elucidate the mechanism of this improvement: an improvement in myocardial reserve or an improvement in peripheral muscular capacity? The main objective of this study is to evaluate the difference in right ventricular contractile reserve before and after cardiorespiratory rehabilitation during stress ultrasound in pulmonary hypertension in 10 patients with pulmonary hypertension.
Investigators
Eligibility Criteria
Inclusion Criteria
- •Major patients
- •Proven pulmonary hypertension: PAPm ≥ 25mmHg, known PH
- •Group 1,3,4 or 5 of the pulmonary hypertension classification
- •Clinical stability \> 1 month clinically determined by clinician
- •NYHA II or III class
- •Signature of informed consent form following appropriate information
- •Patient affiliated to the Social Security System
Exclusion Criteria
- •Associated left heart disease
- •Complex congenital heart disease
- •Acoustic window which does not allow the echocardiography to be performed correctly
- •Permanent cardiac arrhythmia
- •NYHA IV class and NYHA I class
- •Inability to perform at least a minimal effort on an ergometer
- •Unstabilized acute coronary syndrome
- •Compensatory heart failure
- •Disturbances of ventricular rhythm veins, may not be narrowed.
- •Prevalence of high-risk embolic intracardiac thrombus
Outcomes
Primary Outcomes
Improvement of the subpulmonary ITS at effort >20% (presence of a right ventricular contractile reserve) defined by the improvement of the ITS or integral subpulmonary time-speed)
Time Frame: 4 months