Effects of Cardiorespiratory Rehabilitation on the Right Ventricle in Pulmonary Hypertension
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 12
- 试验地点
- 2
- 主要终点
- Improvement of the subpulmonary ITS at effort >20% (presence of a right ventricular contractile reserve) defined by the improvement of the ITS or integral subpulmonary time-speed)
研究概览
简要总结
Clinical improvement has been demonstrated after cardiorespiratory rehabilitation in patients with pulmonary hypertension. Rehabilitation is therefore now part of the recommendations for good practice. However, no data is available to elucidate the mechanism of this improvement: an improvement in myocardial reserve or an improvement in peripheral muscular capacity? The main objective of this study is to evaluate the difference in right ventricular contractile reserve before and after cardiorespiratory rehabilitation during stress ultrasound in pulmonary hypertension in 10 patients with pulmonary hypertension.
研究设计
- 研究类型
- Interventional
- 分配方式
- Na
- 干预模型
- Single Group
- 主要目的
- Other
- 盲法
- None
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Major patients
- •Proven pulmonary hypertension: PAPm ≥ 25mmHg, known PH
- •Group 1,3,4 or 5 of the pulmonary hypertension classification
- •Clinical stability > 1 month clinically determined by clinician
- •NYHA II or III class
- •Signature of informed consent form following appropriate information
- •Patient affiliated to the Social Security System
排除标准
- •Associated left heart disease
- •Complex congenital heart disease
- •Acoustic window which does not allow the echocardiography to be performed correctly
- •Permanent cardiac arrhythmia
- •NYHA IV class and NYHA I class
- •Inability to perform at least a minimal effort on an ergometer
- •Unstabilized acute coronary syndrome
- •Compensatory heart failure
- •Disturbances of ventricular rhythm veins, may not be narrowed.
- •Prevalence of high-risk embolic intracardiac thrombus
- •Prevalence of high-risk embolic intracardiac thrombus
- •Preference of a medium to high abundance peericard-like thinning.
- •Venous thromboembolic venous thromboembolic disease (> 3 months)
- •Left ventricular ejector obstruction (severe and/or symptomatic)
- •Persons under guardianship, under curatorship, protected by law
- •Persons deprived of their liberty
- •Pregnant and parturient women
- •Major not able or unable to express consent
- •Inability to perform cardiac rehabilitation
- •Modynamic instability
- •Follow-up impossible for geographical or psychological reasons
- •Inadequate command of the French language
结局指标
主要结局
Improvement of the subpulmonary ITS at effort >20% (presence of a right ventricular contractile reserve) defined by the improvement of the ITS or integral subpulmonary time-speed)
时间窗: 4 months
次要结局
未报告次要终点